Target Description
| Type | Detail |
|---|---|
| Target ID | T73QZ2 |
| Protein Name | Methylcytosine dioxygenase TET2 |
| Uniprot ID |
Q6N021 |
| Protein Name Alias | EC 1.14.11.n2 |
| Gene ID |
54790 |
| Gene Symbol | TET2 |
| Gene Alias | KIAA1546 |
| TTD | NA |
| Pfam | PF12851 |
| GO |
0003677:DNA binding
0008270:zinc ion binding 0080182:histone H3-K4 trimethylation 0030099:myeloid cell differentiation 0070989:oxidative demethylation 0006493:protein O-linked glycosylation 0007049:cell cycle 0006211:5-methylcytosine catabolic process 0080111:DNA demethylation 0005634:nucleus 0070579:methylcytosine dioxygenase activity 0045944:positive regulation of transcription by RNA polymerase II 0008198:ferrous iron binding |
| PDB | 4NM6 ; 5D9Y ; 5DEU |
| Drugbank | NA |
| KEGG | hsa:54790 |
Related Herbs (Total: 47)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0476 | Can E | 蚕蛾 | Silkworm | Bombyx mori |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0500 | Can Yong | 蚕蛹 | Silkworm chrysalis | Bombyx mori |
| H0757 | Ying Su Ke | 罂粟壳 | Opium poppy pericarp | Papaver somniferum |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H1110 | Gua Lou Zi | 瓜蒌子 | mongolian snakegourd seed | Trichosanthes kirilowii maxim |
| H0083 | Jiu Jie Cha | 九节茶 | Glabrous sarcandra | Sarcandra glabra |
| H0696 | Ya Jiao Ai | 鸭脚艾 | Ghostplant wormwood | Artemisia lactiflora |
| H0004 | Huo Xiang | 藿香 | Patchouli | Pogostemon cablin |
| H0248 | Mi Ying Su Ke | 蜜罂粟壳 | Opium poppy | Papaver somniferum |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0871 | Chuan Duan | 川断 | Teasels | Dipsacus asper |
| H1077 | Bai Hu Jiao | 白胡椒 | white pepper | Piper nigrum |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0495 | Can Sha | 蚕砂 | Silkworm excrement | Bombyx mori |
| H1176 | Hei Hu Jiao | 黑胡椒 | Black pepper | Piper nigrum |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0243 | Mi Kuan Dong Hua | 蜜款冬花 | Common coltsfoot | Tussilago farfara |
| H0595 | Wu Hua Guo | 无花果 | Fig | Ficus carica |
| H0290 | Niu Er Feng | 牛耳枫 | calyx-shaped daphniphyllum fruit | Daphniphyllum calycinum |
| H0572 | Tu Huo Xiang | 土藿香 | Patchouli | Pogostemon cablin |
| H0650 | Chai Hu | 柴胡 | Chinese thorowax | Bupleurum chinense |
| H0756 | Ying Su | 罂粟 | Opium poppy | Papaver somniferum |
| H0714 | Yan Tai Chai Hu | 烟台柴胡 | Chinese thorowax | Bupleurum chinense |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
| H0612 | Cao Shan Hu Jin Gao | 草珊瑚浸膏 | NA | Sarcandra glabra |
| H1088 | Gan Zhe | 甘蔗 | Sweetcane culm | Saccharum sinensis |
| H1120 | Guang Huo Xiang | 广藿香 | Patchouli | Pogostemon cablin |
| H0706 | Yan Hu Suo | 延胡索 | Yanhusuo | Corydalis yanhusuo |
| H0005 | Huo Xiang Ye | 藿香叶 | Patchouli | Pogostemon cablin |
| H0115 | Kuan Dong Hua | 款冬花 | Common coltsfoot | Tussilago farfara |
| H0961 | Dang Yao | 当药 | Chinese swertia | Swertia chinensis |
| H0498 | Si Ji Cai | 四季菜 | Ghostplant wormwood | Artemisia lactiflora |
| H0665 | Chai Hu Shao | 柴胡梢 | Chinese thorowax | Bupleurum chinense |
| H1134 | Bai Jiang Can | 白僵蚕 | Silkworm larva | Bombyx mori |
| H1184 | Bai Lian | 白蔹 | Japanese ampelopsis | Ampelopsis japonica |
| H1133 | Gui Jian Yu | 鬼箭羽 | Winged euonymus | Euonymus alatus |
| H0659 | Chai Hu Jin Gao | 柴胡浸膏 | Chinese thorowax | Bupleurum chinense |
| H1010 | Du Huo Xiang | 杜藿香 | Patchouli | Pogostemon cablin |
| H1204 | Hu Jiao | 胡椒 | Black pepper | Piper nigrum |
| H0490 | Can Jian | 蚕茧 | Silk cocoon | Bombyx mori |
| H0766 | Yu Zhu | 玉竹 | NA | Polygonatum odoratum |
| H0903 | Ci Cai | 荠菜 | Shepherdspurse | Capsella bursa-pastoris |