HIT-result

Target Description

Type	Detail
Target ID	T40MJF
Protein Name	Gamma-aminobutyric acid receptor subunit gamma-1
Uniprot ID	Q8N1C3
Protein Name Alias	GABA(A) receptor subunit gamma-1
Gene ID	2565
Gene Symbol	GABRG1
Gene Alias	NA
TTD	NA
Pfam	PF02932 ; PF02931
GO	0007214:gamma-aminobutyric acid signaling pathway 0051932:synaptic transmission, GABAergic 0004890:GABA-A receptor activity 0007268:chemical synaptic transmission 0098794:postsynapse 0042391:regulation of membrane potential 0032590:dendrite membrane 1902711:GABA-A receptor complex 1904315:transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential 0034707:chloride channel complex 0045211:postsynaptic membrane 0043005:neuron projection 0005887:integral component of plasma membrane 0050811:GABA receptor binding 0005886:plasma membrane 0030594:neurotransmitter receptor activity 0045202:synapse 0034220:ion transmembrane transport 0022851:GABA-gated chloride ion channel activity 0007165:signal transduction 0005237:inhibitory extracellular ligand-gated ion channel activity 0050877:nervous system process 1902476:chloride transmembrane transport 0060078:regulation of postsynaptic membrane potential
PDB	NA
Drugbank	DB01594 ; DB00659 ; DB01558 ; DB00292 ; DB13335 ; DB01189 ; DB01068 ; DB00603 ; DB00404 ; DB01553 ; DB01588 ; DB00818 ; DB00555 ; DB01956 ; DB00690 ; DB01589 ; DB00475 ; DB00898 ; DB13872 ; DB00252 ; DB12404 ; DB00334 ; DB14672 ; DB00753 ; DB09118 ; DB11859 ; DB00241 ; DB01107 ; DB09017 ; DB13643 ; DB00231 ; DB01708 ; DB13837 ; DB01545 ; DB01205 ; DB01236 ; DB00897 ; DB00801 ; DB01544 ; DB14028 ; DB00312 ; DB01489 ; DB00189 ; DB13437 ; DB06579 ; DB01595 ; DB00349 ; DB00794 ; DB11901 ; DB12537 ; DB00186 ; DB01567 ; DB00228 ; DB15489 ; DB00237 ; DB00829 ; DB00306 ; DB01511 ; DB00628 ; DB00683 ; DB01437 ; DB01028 ; DB00402 ; DB00371 ; DB11582 ; DB14715 ; DB00543 ; DB01159 ; DB01043 ; DB01559 ; DB00463 ; DB00842 ; DB09166 ; DB01215 ; DB01587 ; DB00546 ; DB14719
KEGG	hsa:2565

Type

Detail

Target ID

T40MJF

Protein Name

Gamma-aminobutyric acid receptor subunit gamma-1

Uniprot ID

Q8N1C3

Protein Name Alias

GABA(A) receptor subunit gamma-1

Gene ID

2565

Gene Symbol

GABRG1

Gene Alias

TTD

Pfam

PF02932 ; PF02931

0007214:gamma-aminobutyric acid signaling pathway

0051932:synaptic transmission, GABAergic

0004890:GABA-A receptor activity

0007268:chemical synaptic transmission

0098794:postsynapse

0042391:regulation of membrane potential

0032590:dendrite membrane

1902711:GABA-A receptor complex

1904315:transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

0034707:chloride channel complex

0045211:postsynaptic membrane

0043005:neuron projection

0005887:integral component of plasma membrane

0050811:GABA receptor binding

0005886:plasma membrane

0030594:neurotransmitter receptor activity

0045202:synapse

0034220:ion transmembrane transport

0022851:GABA-gated chloride ion channel activity

0007165:signal transduction

0005237:inhibitory extracellular ligand-gated ion channel activity

0050877:nervous system process

1902476:chloride transmembrane transport

0060078:regulation of postsynaptic membrane potential

PDB

Drugbank

DB01594 ; DB00659 ; DB01558 ; DB00292 ; DB13335 ; DB01189 ; DB01068 ; DB00603 ; DB00404 ; DB01553 ; DB01588 ; DB00818 ; DB00555 ; DB01956 ; DB00690 ; DB01589 ; DB00475 ; DB00898 ; DB13872 ; DB00252 ; DB12404 ; DB00334 ; DB14672 ; DB00753 ; DB09118 ; DB11859 ; DB00241 ; DB01107 ; DB09017 ; DB13643 ; DB00231 ; DB01708 ; DB13837 ; DB01545 ; DB01205 ; DB01236 ; DB00897 ; DB00801 ; DB01544 ; DB14028 ; DB00312 ; DB01489 ; DB00189 ; DB13437 ; DB06579 ; DB01595 ; DB00349 ; DB00794 ; DB11901 ; DB12537 ; DB00186 ; DB01567 ; DB00228 ; DB15489 ; DB00237 ; DB00829 ; DB00306 ; DB01511 ; DB00628 ; DB00683 ; DB01437 ; DB01028 ; DB00402 ; DB00371 ; DB11582 ; DB14715 ; DB00543 ; DB01159 ; DB01043 ; DB01559 ; DB00463 ; DB00842 ; DB09166 ; DB01215 ; DB01587 ; DB00546 ; DB14719

KEGG

hsa:2565

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0891	Chuan Xin Lian Ye	穿心莲叶	Powder of green chiretta leaves	Andrographis herba
H0527	Tao	桃	Peach	Prunus persica
H1251	Huang Qin	黄芩	Root of Baikal skullcaap	Scutellaria baicalensis
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H0925	Da Fu Zi	大腹子	Areca palm	Areca catechu
H0531	Tao Zhi	桃枝	Peach juvenile branch	Prunus persica
H0408	Bing Lang	槟榔	Betenutpalm	Areca catechu
H0310	Pian Qin	片芩	Scutellaria amoena	Scutellaria baicalensis
H0033	Jiao Bing Lang	焦槟榔	Charred areca seed	Semen arecae preparata
H0706	Yan Hu Suo	延胡索	Yanhusuo	Corydalis yanhusuo
H1253	Huang Qin Jin Gao Fen	黄芩浸膏粉	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0529	Tao Ren	桃仁	Peach kernel	Prunus persica
H1252	Huang Qin Jin Gao	黄芩浸膏	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0633	Xia Tian Wu	夏天无	Decumbent corydalis	Corydalis decumbens
H1254	Huang Qin Tan	黄芩炭	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H1015	Du Zhong	杜仲	Eucommia	Eucommia ulmoides
H1017	Du Zhong Ye	杜仲叶	Eucommia leaf	Eucommia ulmoides
H1016	Du Zhong Tan	杜仲炭	Eucommia	Eucommia ulmoides
H0530	Tao Ren Shuang	桃仁霜	Peach kernel	Prunus persica
H0626	Xi Nan Huang Qin	西南黄芩	Yunnan skullcap	Scutellaria amoena

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 20)