Compound Description
| ID: C1220 | Common name: Catechin |
| IUPAC: 2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol | CAS: NA |
| Chembl ID: CHEMBL206452 | Pubchem ID: CID:1203 |
| Formula: C15H14O6 | TCM-ID: TCMC878 |
| Smiles: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O | |
| Alias:
NA
|
Structure:
|
Related Targets (Total: 22)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
A | 1 Reference(s) |
| T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
A | 1 Reference(s) |
| T53RK9 | T-cell surface glycoprotein CD4 | CD4 |
P01730 |
A | 1 Reference(s) |
| T92Q77 | Type I iodothyronine deiodinase | DIO1 |
P49895 |
B | 1 Reference(s) |
| T03CZ8 | Catechol O-methyltransferase | COMT |
P21964 |
B | 1 Reference(s) |
| T99EYH | Lipoprotein lipase | LPL |
P06858 |
B | 1 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
B | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
B | 1 Reference(s) |
| T99W15 | Pancreatic triacylglycerol lipase | PNLIP |
P16233 |
B | 1 Reference(s) |
| T56TXY | Polyunsaturated fatty acid 5-lipoxygenase | ALOX5 |
P09917 |
B | 1 Reference(s) |
| T24LXT | G2/mitotic-specific cyclin-B1 | CCNB1 |
P14635 |
B | 1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
B | 1 Reference(s) |
| T86UXL | Cyclin-A2 | CCNA2 |
P20248 |
B | 1 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
B | 2 Reference(s) |
| T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 |
P04179 |
B | 1 Reference(s) |
| T00H7Q | Neutrophil cytosol factor 1 | NCF1 |
P14598 |
C | 1 Reference(s) |
| T00EP2 | Tissue-type plasminogen activator | PLAT |
P00750 |
C | 1 Reference(s) |
| T84P70 | Urokinase-type plasminogen activator | PLAU |
P00749 |
C | 1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
C | 1 Reference(s) |
| T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
C | 1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
C | 1 Reference(s) |
| T35QZO | Cytochrome c | CYCS |
P99999 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 92)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0858 | Zong Lv Pi | 棕榈皮 | Fortune windmillpalm | Trachycarpus fortunei |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0926 | Da Huang | 大黄 | Medicinal rhubarb | Rheum officinale |
| H0043 | Jie Zi | 芥子 | India mustard seed | Brassica juncea |
| H1036 | Fen Dan Pi | 粉丹皮 | Tree peony bark | Paeonia suffruticosa |
| H0857 | Zong Ban Tan | 棕板炭 | NA | Trachycarpus fortunei |
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H0365 | Rou Dou Kou | 肉豆蔻 | Common nutmeg | Myristica fragrans |
| H0932 | Ba Qia | 菝葜 | Chinaroot greenbrier | Smilax china |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0860 | Zong Lv Zi | 棕榈子 | NA | Trachycarpus fortunei |
| H0764 | Yu Xing Cao | 鱼腥草 | Heartleaf houttuynia | Houttuynia cordata |
| H0979 | Di Yu | 地榆 | Garden burnet | Sanguisorba officinalis |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0181 | Luo Bu Ma | 罗布麻 | Dogbane | Apocynum venetum |
| H0601 | Wu Mei | 乌梅 | Japanese apricot | Prunus mume |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H0818 | Zhi Zi | 栀子 | Cape jasmine fruit | Gardenia jasminoides |
| H1068 | Bai He Liu Jin Gao | 百合流浸膏 | Lily | Lilium brownii |
| H1053 | Fu Ling | 茯苓 | Indian bread | Wolfiporia cocos |
| H1034 | Fei Yang Cao | 飞杨草 | NA | Euphorbia hirta |
| H0765 | Chi Dou | 赤豆 | Assuki bean | Vigna angularis |
| H0773 | Chi Fu Ling | 赤茯苓 | light red indian bread | Wolfiporia cocos |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
| H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0927 | Da Huang Jin Gao | 大黄浸膏 | Medicinal rhubarb | Rheum officinale |
| H0825 | Zhu Fu Shen | 朱茯神 | Indian bread with pine | Poria cocos |
| H1099 | Gou Teng | 钩藤 | Sharpleaf gambirplant | Uncaria rhynchophylla |
| H1152 | Bai Jie Zi | 白芥子 | White mustard seed | Sinapis alba |
| H1137 | Gui Yuan | 桂圆 | NA | Dimocarpus longan |
| H0152 | Ling Zhi Jin Gao | 灵芝浸膏 | NA | Ganoderma lucidum |
| H0485 | Shui Hong Hua | 水红花 | Fructus polygoni orientalis | Polygonum orientale |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H0424 | Shan Zhi | 山栀 | Cape jasmine | Gardenia jasminoides |
| H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0519 | Suo Yang | 锁阳 | Songaria cynomorium | Cynomorium songaricum |
| H1133 | Gui Jian Yu | 鬼箭羽 | Winged euonymus | Euonymus alatus |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
| H0574 | Cao Dou Kou | 草豆蔻 | Katsumada galangal | Alpinia katsumadai |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0166 | Long Kui | 龙葵 | Black nightshade | Solanum nigrum |
| H0777 | Zao Jia | 皂荚 | Chinese honeylocust | Gleditsia sinensis |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0980 | Di Yu Tan | 地榆炭 | Garden burnet | Sanguisorba officinalis |
| H0486 | Shui Hong Hua Ye | 水红花叶 | Fructus polygoni orientalis | Polygonum orientale |
| H0068 | Jin Ying Zi Rou | 金樱子肉 | Cherokee rose seed | Rosa laevigata |
| H0925 | Da Fu Zi | 大腹子 | Areca palm | Areca catechu |
| H1214 | Hua Jiao | 花椒 | Bunge pricklyash | Zanthoxylum bungeanum |
| H0779 | Zao Jiao Zhen | 皂角针 | Chinese honeylocust spine | Gleditsia sinensis |
| H0928 | Da Huang Liu Jin Gao | 大黄流浸膏 | Medicinal rhubarb | Rheum officinale |
| H0408 | Bing Lang | 槟榔 | Betenutpalm | Areca catechu |
| H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H0153 | Ling Zhi(1) | 灵芝 | Lucid ganoderma | Ganoderma lucidum |
| H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
| H1184 | Bai Lian | 白蔹 | Japanese ampelopsis | Ampelopsis japonica |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
| H0856 | Zong Ban | 棕板 | NA | Trachycarpus fortunei |
| H0195 | Ma Chi Xian | 马齿苋 | Purslane | Portulaca oleracea |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H1102 | Gu Sui Bu | 骨碎补 | Fortune’s drynaria rhizome | Drynaria fortunei |
| H0472 | Shu Da Huang | 熟大黄 | NA | Rheum palmatum |
| H1217 | Bai Mei Hua | 白梅花 | Japanese apricot flower | Prunus mume |
| H1213 | Hu Zhang | 虎杖 | Japanese fleeceflower | Polygonum cuspidatum |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0698 | Ya Zao | 牙皂 | Chinese honeylocust abnormal fruit | Gleditsia sinensis |
| H0067 | Jin Ying Zi | 金樱子 | Cherokee rose seed | Rosa laevigata |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
| H1029 | Fang Er Cha | 方儿茶 | khair in hindi | Senegalia catechu |
| H0939 | Da Xue Teng | 大血藤 | Sargentgloryvine | Sargentodoxa cuneata |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0602 | Wu Mei Rou | 乌梅肉 | Ebony | Prunus mume |
| H0819 | Zhi Zi Jin Gao | 栀子浸膏 | Cape jasmine fruit | Gardenia jasminoides |
| H0069 | Jin Ying Zi Ti Qu Ye | 金樱子提取液 | Cherokee rose seed | Rosa laevigata |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0582 | Cao Dou Kou Ren | 草豆蔻仁 | Katsumada galangal | Alpinia katsumadai |
| H0007 | Huo Xue Teng | 活血藤 | NA | Sargentodoxa cuneata |
| H1061 | Bai He | 百合 | Lily | Lilium brownii |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
Ckey description of the interaction between compound and target