HIT-result

Target Description

Type	Detail
Target ID	T78KL2
Protein Name	Collagen alpha-1(III) chain
Uniprot ID	P02461
Protein Name Alias	NA
Gene ID	1281
Gene Symbol	COL3A1
Gene Alias	NA
TTD	NA
Pfam	PF01410 ; PF00093 ; PF01391
GO	0048407:platelet-derived growth factor binding 0030168:platelet activation 0005178:integrin binding 0031012:extracellular matrix 0005586:collagen type III trimer 0005615:extracellular space 0043588:skin development 0018149:peptide cross-linking 0007229:integrin-mediated signaling pathway 0005201:extracellular matrix structural constituent 0007507:heart development 0030199:collagen fibril organization 0050777:negative regulation of immune response 0046872:metal ion binding 2001223:negative regulation of neuron migration 0050776:regulation of immune response 0001501:skeletal system development 0005576:extracellular region 0062023:collagen-containing extracellular matrix 0035025:positive regulation of Rho protein signal transduction 0007160:cell-matrix adhesion 0009314:response to radiation 0034097:response to cytokine 0097435:supramolecular fiber organization 0030020:extracellular matrix structural constituent conferring tensile strength 0021987:cerebral cortex development 0002020:protease binding 0009612:response to mechanical stimulus 0007179:transforming growth factor beta receptor signaling pathway 0042060:wound healing 0030198:extracellular matrix organization 0005788:endoplasmic reticulum lumen
PDB	6FZV ; 4AEJ ; 2V53 ; 3DMW ; 4GYX ; 4AK3 ; 4AE2 ; 6FZW
Drugbank	DB00048
KEGG	hsa:1281

Type

Detail

Target ID

T78KL2

Protein Name

Collagen alpha-1(III) chain

Uniprot ID

P02461

Protein Name Alias

Gene ID

1281

Gene Symbol

COL3A1

Gene Alias

TTD

Pfam

PF01410 ; PF00093 ; PF01391

0048407:platelet-derived growth factor binding

0030168:platelet activation

0005178:integrin binding

0031012:extracellular matrix

0005586:collagen type III trimer

0005615:extracellular space

0043588:skin development

0018149:peptide cross-linking

0007229:integrin-mediated signaling pathway

0005201:extracellular matrix structural constituent

0007507:heart development

0030199:collagen fibril organization

0050777:negative regulation of immune response

0046872:metal ion binding

2001223:negative regulation of neuron migration

0050776:regulation of immune response

0001501:skeletal system development

0005576:extracellular region

0062023:collagen-containing extracellular matrix

0035025:positive regulation of Rho protein signal transduction

0007160:cell-matrix adhesion

0009314:response to radiation

0034097:response to cytokine

0097435:supramolecular fiber organization

0030020:extracellular matrix structural constituent conferring tensile strength

0021987:cerebral cortex development

0002020:protease binding

0009612:response to mechanical stimulus

0007179:transforming growth factor beta receptor signaling pathway

0042060:wound healing

0030198:extracellular matrix organization

0005788:endoplasmic reticulum lumen

PDB

6FZV ; 4AEJ ; 2V53 ; 3DMW ; 4GYX ; 4AK3 ; 4AE2 ; 6FZW

Drugbank

DB00048

KEGG

hsa:1281

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Name: (+/-)Nicotine

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Name: aldosterone

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Name: danshensu

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Name: Colchicine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0925	Da Fu Zi	大腹子	Areca palm	Areca catechu
H0560	Cao Bei Mu	草贝母	Indian iphigenia	Iphigenia indica
H1176	Hei Hu Jiao	黑胡椒	Black pepper	Piper nigrum
H0958	Dang Shen	党参	Pilose asiabell	Codonopsis pilosula
H0960	Dang Shen Qing Gao	党参清膏	Root of hairy asiabell	Codonopsis pilosula
H0275	Mu Zei	木贼	Common scouring rush	Equisetum hiemale
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0132	Li Lu	藜芦	Black falsehellebore	Veratrum nigrum
H1077	Bai Hu Jiao	白胡椒	white pepper	Piper nigrum
H0258	Mo Han Lian	墨旱莲	Yerbadetajo	Eclipta prostrata
H1204	Hu Jiao	胡椒	Black pepper	Piper nigrum
H0408	Bing Lang	槟榔	Betenutpalm	Areca catechu

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 13)