Target Description

Type Detail
Target ID T01P7T
Protein Name Retinoic acid receptor RXR-beta
Uniprot ID P28702
Protein Name Alias Nuclear receptor subfamily 2 group B member 2;  Retinoid X receptor beta
Gene ID 6257
Gene Symbol RXRB
Gene Alias NR2B2
TTD T60077: Successful target
Pfam PF00105 ; PF00104
GO
1990837:sequence-specific double-stranded DNA binding

0030522:intracellular receptor signaling pathway

0004879:nuclear receptor activity

0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding

0048856:anatomical structure development

0030154:cell differentiation

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0005654:nucleoplasm

0005737:cytoplasm

0045893:positive regulation of transcription, DNA-templated

0008270:zinc ion binding

0090575:RNA polymerase II transcription regulator complex

0000785:chromatin

0045944:positive regulation of transcription by RNA polymerase II

0005634:nucleus

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0003707:steroid hormone receptor activity

0032526:response to retinoic acid

0006367:transcription initiation from RNA polymerase II promoter

0048384:retinoic acid receptor signaling pathway

0044323:retinoic acid-responsive element binding

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0006357:regulation of transcription by RNA polymerase II

PDB 1H9U ; 5KYA ; 5KYJ ; 1UHL ; 5I4V ; 5HJP ; 7A78
Drugbank DB00926 ; DB02746 ; DB07929 ; DB00799 ; DB03756 ; DB00523 ; DB01941 ; DB00412 ; DB00307 ; DB00755 ; DB07080 ; DB00210 ; DB00459 ; DB08175 ; DB01393
KEGG hsa:6257

Related Compounds  (Total: 1)

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C0639
Name: (+/-)Nicotine


Related Herbs  (Total: 11)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0925 Da Fu Zi大腹子 Areca palmAreca catechu
H1176 Hei Hu Jiao黑胡椒 Black pepperPiper nigrum
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H0275 Mu Zei木贼 Common scouring rushEquisetum hiemale
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1077 Bai Hu Jiao白胡椒 white pepperPiper nigrum
H0258 Mo Han Lian墨旱莲 YerbadetajoEclipta prostrata
H1204 Hu Jiao胡椒 Black pepperPiper nigrum
H0408 Bing Lang槟榔 BetenutpalmAreca catechu