Target Description

Type Detail
Target ID T91F6Z
Protein Name Integrin alpha-L
Uniprot ID P20701
Protein Name Alias CD11 antigen-like family member A;  Leukocyte adhesion glycoprotein LFA-1 alpha chain;  LFA-1A;  Leukocyte function-associated molecule 1 alpha chain;  CD antigen CD11a
Gene ID 3683
Gene Symbol ITGAL
Gene Alias CD11A
TTD T35640: Successful target
Pfam PF01839 ; PF00092 ; PF08441 ; PF00357
GO
0070062:extracellular exosome

0007229:integrin-mediated signaling pathway

0016020:membrane

0050900:leukocyte migration

0009986:cell surface

0008305:integrin complex

0035683:memory T cell extravasation

0030369:ICAM-3 receptor activity

0046872:metal ion binding

0002291:T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

0050776:regulation of immune response

0007159:leukocyte cell-cell adhesion

0044877:protein-containing complex binding

0005886:plasma membrane

0007160:cell-matrix adhesion

0043312:neutrophil degranulation

0098609:cell-cell adhesion

0043113:receptor clustering

0034687:integrin alphaL-beta2 complex

0030198:extracellular matrix organization

0006954:inflammatory response

0050839:cell adhesion molecule binding

0035579:specific granule membrane

0007155:cell adhesion

0007165:signal transduction

0016032:viral process

0006909:phagocytosis

PDB 3M6F ; 1CQP ; 6BXF ; 5E6R ; 1RD4 ; 3BQN ; 5E6U ; 1DGQ ; 1ZOO ; 3BQM ; 6CKB ; 1MQA ; 1MQ8 ; 3TCX ; 6BXJ ; 1XUO ; 1XDD ; 1MQ9 ; 3BN3 ; 2M3E ; 1XDG ; 3HI6 ; 3EOB ; 5E6S ; 1LFA ; 2O7N ; 1ZOP ; 2ICA ; 2K8O ; 1ZON ; 3F74 ; 6BXB ; 1T0P ; 1IJ4 ; 3E2M ; 3EOA ; 4IXD ; 1MJN ; 3F78
Drugbank DB04724 ; DB01098 ; DB08860 ; DB00227 ; DB03932 ; DB02177 ; DB06972 ; DB00641 ; DB07486 ; DB00095 ; DB11611 ; DB00098
KEGG hsa:3683

Related Compounds  (Total: 2)

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C0413
Name: Spermine
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C0639
Name: (+/-)Nicotine


Related Herbs  (Total: 12)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1204 Hu Jiao胡椒 Black pepperPiper nigrum
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H0925 Da Fu Zi大腹子 Areca palmAreca catechu
H0258 Mo Han Lian墨旱莲 YerbadetajoEclipta prostrata
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H1176 Hei Hu Jiao黑胡椒 Black pepperPiper nigrum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1077 Bai Hu Jiao白胡椒 white pepperPiper nigrum
H0194 Ma Bing Lang马槟榔 Masaikai caperCapparis masaikai
H0408 Bing Lang槟榔 BetenutpalmAreca catechu
H0275 Mu Zei木贼 Common scouring rushEquisetum hiemale