Compound Description

ID:   C0085 Common name:   Fraxetin
IUPAC:  7,8-dihydroxy-6-methoxychromen-2-one CAS:  CAS:574-84-5
Chembl ID:   CHEMBL54909 Pubchem ID:   CID:5273569
Formula:  C10H8O5 TCM-ID:  TCMC1188
Smiles:  COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)O
Alias:

Coumarin, 7,8-dihydroxy-6-methoxy-;

Fraxetin;

7,8-Dihydroxy-6-methoxy-2H-1-benzopyran-2-one;

6-Methoxy-7,8-dihydroxycoumarin;

7,8-Dihydroxy-6-methoxycoumarin;

Fratexin;

Fraxetol
Structure:

Related Targets  (Total: 6)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
A 1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
B 1 Reference(s)
T38T1U Caspase-8CASP8 Q14790
B 1 Reference(s)
T85U8U Caspase-3CASP3 P42574
B 1 Reference(s)
T31SX8 Bone morphogenetic protein 2BMP2 P12643
B 1 Reference(s)
T19BO9 Bone morphogenetic protein 4BMP4 P12644
B 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 4)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0612 Cao Shan Hu Jin Gao草珊瑚浸膏 NASarcandra glabra
H0335 Qin Pi秦皮 bark of largeleaf chinese ashCortex fraxini
H0083 Jiu Jie Cha九节茶 Glabrous sarcandraSarcandra glabra
H1236 Huang Hua黄花 NAHemerocallis citrina