Compound Description
| ID: C0118 | Common name: Hesperetin |
| IUPAC: (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one | CAS: CAS:520-33-2 |
| Chembl ID: CHEMBL399121 | Pubchem ID: CID:72281 |
| Formula: C16H14O6 | TCM-ID: TCMC1320 |
| Smiles: COc1ccc(cc1O)[C@@H]1CC(=O)c2c(O1)cc(cc2O)O | |
| Alias:
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)-;
Flavanone, 3',5,7-trihydroxy-4'-methoxy-; Hesperetin; (2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; (-)-Hesperetin; (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one; (S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 3',5,7-Trihydroxy-4'-methoxyflavanone; 5,7,3'-Trihydroxy-4'-methoxyflavanone; Eriodictyol 4'-monomethyl ether; Hesperitin; NSC 57654 |
Structure:
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Related Targets (Total: 3)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
A | 2 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
A | 1 Reference(s) |
| T88LSZ | Aromatase | CYP19A1 |
P11511 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 28)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0314 | Pu Gong Ying | 蒲公英 | Mongolian dandelion | Taraxacum mongolicum |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0111 | Ku Shen | 苦参 | Lightyellow sophora | Sophora flavescens |
| H0265 | Mu Da Qing Ye | 木大青叶 | Indigo-coloured woad leaf equivalent | Isatis indigotica |
| H0315 | Pu Gong Ying Jin Gao | 蒲公英浸膏 | Mongolian dandelion | Taraxacum mongolicum |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0137 | Ban Lan Gen | 板蓝根 | Indigowoad root | Isatis indigotica |
| H0152 | Ling Zhi Jin Gao | 灵芝浸膏 | NA | Ganoderma lucidum |
| H0937 | Da Qing Ye | 大青叶 | Indigo-coloured woad leaf | Isatis indigotica |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0131 | Ban Lan | 板蓝 | Indigowoad root | Isatis indigotica |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H1244 | Huang Miao | 黄苗 | NA | Taraxacum mongolicum |
| H0575 | Tu Ku Shen | 土苦参 | all-grass of hooker winghead | Sophora flavescens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
| H0263 | Mu Ban Lan Gen | 木板蓝根 | Indigowoad root | Isatis indigotica |
| H0153 | Ling Zhi(1) | 灵芝 | Lucid ganoderma | Ganoderma lucidum |
| H0651 | Xiang Yuan | 香橼 | Wilson citron | Citrus medica |
| H0072 | Jing Jie | 荆芥 | Fineleaf schizonepeta | Schizonepeta tenuifolia |
| H0533 | Teng Ku Shen | 藤苦参 | NA | Sophora flavescens |
| H0219 | Man Shan Hong | 满山红 | Dahurian rhododendron | Rhododendron dauricum |
| H0166 | Long Kui | 龙葵 | Black nightshade | Solanum nigrum |
| H0652 | Xiang Yuan Pi | 香橼皮 | Wilson citron | Citrus medica |
| H0073 | Jing Jie Sui | 荆芥穗 | NA | Schizonepetae spica |
Ckey description of the interaction between compound and target