HIT-result

ID: C0142	Common name: Indirubin
IUPAC: (3Z)-3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one	CAS: CAS:479-41-4
Chembl ID: CHEMBL1276127	Pubchem ID: CID:5318433
Formula: C16H10N2O2	TCM-ID: TCMC1371
Smiles: O=C1/C(=C\2/C(=Nc3c2cccc3)O)/Nc2c1cccc2
Alias: Indirubin; [Δ2,3'-Biindoline]-2',3-dione; 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one; C.I. 73200; Couroupitine B; Indigo red; Indigopurpurin; NSC 105327	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T32R5L	Cyclin-dependent kinase 9	CDK9	P50750	A	1 Reference(s)
T84W8G	Aryl hydrocarbon receptor	AHR	P35869	A	1 Reference(s)
T10AWW	M-phase inducer phosphatase 2	CDC25B	P30305	C	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0137	Ban Lan Gen	板蓝根	Indigowoad root	Isatis indigotica
H0265	Mu Da Qing Ye	木大青叶	Indigo-coloured woad leaf equivalent	Isatis indigotica
H0683	Xiu Xian Ju	绣线菊	Japanese spiraea	Spiraea japonica
H0263	Mu Ban Lan Gen	木板蓝根	Indigowoad root	Isatis indigotica
H0937	Da Qing Ye	大青叶	Indigo-coloured woad leaf	Isatis indigotica
H0131	Ban Lan	板蓝	Indigowoad root	Isatis indigotica
H0669	Xie Bai	薤白	Longstamen onion	Allium macrostemon

Compound Description

Related Targets (Total: 3)

Related Herbs (Total: 7)