HIT-result

Target Description

Type	Detail
Target ID	T10AWW
Protein Name	M-phase inducer phosphatase 2
Uniprot ID	P30305
Protein Name Alias	EC 3.1.3.48; Dual specificity phosphatase Cdc25B
Gene ID	994
Gene Symbol	CDC25B
Gene Alias	CDC25HU2
TTD	T46365: Clinical Trial target
Pfam	PF00581 ; PF06617
GO	0005813:centrosome 0010971:positive regulation of G2/M transition of mitotic cell cycle 0110032:positive regulation of G2/MI transition of meiotic cell cycle 0006468:protein phosphorylation 0007144:female meiosis I 0005829:cytosol 0045931:positive regulation of mitotic cell cycle 0004725:protein tyrosine phosphatase activity 0005654:nucleoplasm 0000278:mitotic cell cycle 0000922:spindle pole 0005737:cytoplasm 0005634:nucleus 0019901:protein kinase binding 0000086:G2/M transition of mitotic cell cycle 0008284:positive regulation of cell population proliferation 0032467:positive regulation of cytokinesis 0001556:oocyte maturation 0051301:cell division 0045860:positive regulation of protein kinase activity
PDB	1YMK ; 1QB0 ; 1YMD ; 1CWR ; 2A2K ; 2UZQ ; 3FQU ; 4WH7 ; 1YM9 ; 1YS0 ; 2IFV ; 1CWS ; 3FQT ; 4WH9 ; 1CWT ; 2IFD ; 1YML
Drugbank	DB03661
KEGG	hsa:994

Type

Detail

Target ID

T10AWW

Protein Name

M-phase inducer phosphatase 2

Uniprot ID

P30305

Protein Name Alias

EC 3.1.3.48; Dual specificity phosphatase Cdc25B

Gene ID

994

Gene Symbol

CDC25B

Gene Alias

CDC25HU2

TTD

T46365: Clinical Trial target

Pfam

PF00581 ; PF06617

0005813:centrosome

0010971:positive regulation of G2/M transition of mitotic cell cycle

0110032:positive regulation of G2/MI transition of meiotic cell cycle

0006468:protein phosphorylation

0007144:female meiosis I

0005829:cytosol

0045931:positive regulation of mitotic cell cycle

0004725:protein tyrosine phosphatase activity

0005654:nucleoplasm

0000278:mitotic cell cycle

0000922:spindle pole

0005737:cytoplasm

0005634:nucleus

0019901:protein kinase binding

0000086:G2/M transition of mitotic cell cycle

0008284:positive regulation of cell population proliferation

0032467:positive regulation of cytokinesis

0001556:oocyte maturation

0051301:cell division

0045860:positive regulation of protein kinase activity

PDB

1YMK ; 1QB0 ; 1YMD ; 1CWR ; 2A2K ; 2UZQ ; 3FQU ; 4WH7 ; 1YM9 ; 1YS0 ; 2IFV ; 1CWS ; 3FQT ; 4WH9 ; 1CWT ; 2IFD ; 1YML

Drugbank

DB03661

KEGG

hsa:994

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0137	Ban Lan Gen	板蓝根	Indigowoad root	Isatis indigotica
H0265	Mu Da Qing Ye	木大青叶	Indigo-coloured woad leaf equivalent	Isatis indigotica
H0277	Nan Ban Lan Gen	南板蓝根	Indigowoad root	Baphicacanthus cusia
H0683	Xiu Xian Ju	绣线菊	Japanese spiraea	Spiraea japonica
H0263	Mu Ban Lan Gen	木板蓝根	Indigowoad root	Isatis indigotica
H0937	Da Qing Ye	大青叶	Indigo-coloured woad leaf	Isatis indigotica
H0131	Ban Lan	板蓝	Indigowoad root	Isatis indigotica
H0669	Xie Bai	薤白	Longstamen onion	Allium macrostemon
H0339	Qing Dai	青黛	Natural indigo	Indigo naturalis
H0278	Nan Ban Lan Gen Jin Gao Fen	南板蓝根浸膏粉	Indigowoad root	Baphicacanthus cusia

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 10)