Compound Description
| ID: C0159 | Common name: Isovitexin |
| IUPAC: 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one | CAS: CAS:38953-85-4 |
| Chembl ID: CHEMBL465360 | Pubchem ID: CID:162350 |
| Formula: C21H20O10 | TCM-ID: TCMC1418 |
| Smiles: C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)C4C(C(C(C(O4)CO)O)O)O)O)O | |
| Alias:
Flavone, 6-β-D-glucopyranosyl-4',5,7-trihydroxy-;
Homovitexin; 6-β-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 6-C-Glucosylapigenin; 6-C-β-D-Glucopyranosylapigenin; Apigenin 6-C-β-D-glucoside; Apigenin 6-C-β-glucopyranoside; Apigenin-6-C-glucoside; Apigenin-6-C-β-D-glucopyranoside; Avroside; Isoavroside; Isovitexin; Isovitexin (C-6 isomer); Saponaretin |
Structure:
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Related Targets (Total: 4)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T83F53 | Forkhead box protein M1 | FOXM1 |
Q08050 |
A | 1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
B | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
B | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
B | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 44)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0765 | Chi Dou | 赤豆 | Assuki bean | Vigna angularis |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0468 | Shi Wei | 石韦 | Japanese felt fern frond | Pyrrosia lingua |
| H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0314 | Pu Gong Ying | 蒲公英 | Mongolian dandelion | Taraxacum mongolicum |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0315 | Pu Gong Ying Jin Gao | 蒲公英浸膏 | Mongolian dandelion | Taraxacum mongolicum |
| H1138 | Bai Jiang Cao | 败酱草 | All - grass of dahurian patrinia | Thlaspi arvense |
| H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H1124 | Guang Jin Qian Cao | 广金钱草 | Snowbellleaf tickclover | Desmodium styracifolium |
| H0234 | Mao Mei Gen | 茅莓根 | NA | Rubus parvifolius |
| H0020 | Ji Yan Cao | 鸡眼草 | Striate kummerowia | Kummerowia striata |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0229 | Mao Da Ding Cao | 毛大丁草 | Pilose gerbera | Gerbera piloselloides |
| H1211 | Bai Mei | 白眉 | pilose gerbera herb | Gerbera piloselloides |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0361 | Ren Zi Cao | 人字草 | Herb of twinleaf zornia | Kummerowia striata |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0362 | Rong Shu Xu | 榕树须 | Banyan | Ficus microcarpa |
| H0524 | Tan Xiang | 檀香 | Sandalwood | Santalum album |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0854 | Zi Wei Gen Pi | 紫葳根皮 | NA | Campsis grandiflora |
| H0339 | Qing Dai | 青黛 | Natural indigo | Indigo naturalis |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0363 | Rong Shu Ye | 榕树叶 | Banyan | Ficus microcarpa |
| H1244 | Huang Miao | 黄苗 | NA | Taraxacum mongolicum |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
| H1220 | Hua Xiang Shu Guo | 化香树果 | NA | Platycarya strobilacea |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0700 | Ya Zhi Cao | 鸭跖草 | Common dayflower | Commelina communis |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H1221 | Hua Xiang Shu Guo Xu | 化香树果序 | NA | Platycarya strobilacea |
| H1128 | Bai Jiang | 败酱 | Whiteflower patrinia | Patrinia villosa |
| H1034 | Fei Yang Cao | 飞杨草 | NA | Euphorbia hirta |
| H0416 | Shan Shen | 山参 | NA | Panax ginseng |
| H0989 | Ding Kui Cao | 丁葵草 | Herb of twinleaf zornia | Kummerowia striata |
| H0954 | Dan Zhu Ye | 淡竹叶 | Common lophatherum | Lophatherum gracile |
Ckey description of the interaction between compound and target