Compound Description
| ID: C0182 | Common name: Levothyroxine |
| IUPAC: (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid | CAS: CAS:51-48-9 |
| Chembl ID: CHEMBL1624 | Pubchem ID: CID:5819 |
| Formula: C15H11I4NO4 | TCM-ID: TCMC1477 |
| Smiles: OC(=O)[C@H](Cc1cc(I)c(c(c1)I)Oc1cc(I)c(c(c1)I)O)N | |
| Alias:
Thyroxine, L-;
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine; (-)-Thyroxine; 3,3',5,5'-Tetraiodo-L-thyronine; Henning; L-T4; L-Thyroxin; L-Thyroxine; Levothyroxine; Levotiron; NSC 36397; SK&F 1-6528; T4 (hormone); THX; Tetraiodothyronine; Thyrax; Thyreoideum; Thyroxin; Thyroxinal; Thyroxine |
Structure:
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Related Targets (Total: 2)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T89GFN | Macrophage migration inhibitory factor | MIF |
P14174 |
A | 2 Reference(s) |
| T04PM9 | Transthyretin | TTR |
P02766 |
B | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 8)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0488 | Shui Niu Jiao Gan Jin Gao | 水牛角干浸膏 | Buffalo horn | Bubalus bubalis |
| H0489 | Shui Niu Jiao Nong Suo Fen | 水牛角浓缩粉 | Buffalo horn | Bubalus bubalis |
| H0487 | Shui Niu Jiao | 水牛角 | Buffalo horn | Bubalus bubalis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0293 | Niu Jiao Tan | 牛角炭 | Buffalo horn | Bubalus bubalis |
| H0292 | Niu Jiao Jian Fen | 牛角尖粉 | Buffalo horn | Bubalus bubalis |
| H0291 | Niu Jiao Fen | 牛角粉 | Buffalo horn | Bubalus bubalis |
Ckey description of the interaction between compound and target