Compound Description

ID:   C0254 Common name:   Nordihydroguaiaretic Acid
IUPAC:  4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol CAS:  CAS:500-38-9
Chembl ID:   CHEMBL52 Pubchem ID:   CID:4534
Formula:  C18H22O4 TCM-ID:  TCMC1757
Smiles:  CC(C(Cc1ccc(c(c1)O)O)C)Cc1ccc(c(c1)O)O
Alias:

Pyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di-;

4,4'-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol];

1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane;

4,4'-(2,3-Dimethyl-1,4-butanediyl)bis(pyrocatechol);

4,4'-(2,3-Dimethyltetramethylene)dipyrocatechol;

4-[4-(3,4-Dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol;

Butane, 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethyl-;

Dihydronorguaiaretic acid;

Dinorguaiaretic acid, dihydro-;

NDGA;

NSC 4291;

Nordihydroguaiaretic acid;

Norguaiaretic acid, dihydro-;

β,γ-Dimethyl-α,δ-bis(3,4-dihydroxyphenyl)butane
Structure:

Related Targets  (Total: 6)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T42PUG Solute carrier family 2, facilitated glucose transporter member 1SLC2A1 P11166
A 1 Reference(s)
T89N0J Protein-lysine 6-oxidaseLOX P28300
A 4 Reference(s)
T55WN8 Proteinase-activated receptor 2F2RL1 P55085
A 1 Reference(s)
T60E54 Endonuclease 8-like 2NEIL2 Q969S2
C 1 Reference(s)
T68OIU CREB-regulated transcription coactivator 1CRTC1 Q6UUV9
C 2 Reference(s)
T64UH1 Nitric oxide synthase, endothelialNOS3 P29474
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 5)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0605 Wu Wei Zi五味子 Chinese magnoliavineSchisandra chinensis
H0608 Wu Wei Zi Jin Gao五味子浸膏 Five-flavor berrySchisandra chinensis
H0609 Wu Wei Zi Liu Jin Gao五味子流浸膏 Five-flavor berrySchisandra chinensis
H0607 Wu Wei Zi Jin Chu Wu五味子浸出物 Five-flavor berrySchisandra chinensis
H0606 Wu Wei Zi Chun Jin Gao五味子醇浸膏 Five-flavor berrySchisandra chinensis