Compound Description
| ID: C0302 | Common name: Phloretin |
| IUPAC: 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one | CAS: CAS:60-82-2 |
| Chembl ID: CHEMBL45068 | Pubchem ID: CID:4788 |
| Formula: C15H14O5 | TCM-ID: TCMC1878 |
| Smiles: Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O | |
| Alias:
Phloretin;
Propiophenone, 2',4',6'-trihydroxy-3-(p-hydroxyphenyl)-; 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone; 2',4',6'-Trihydroxy-3-(4-Hydroxyphenyl)propiophenone; 2',4',6'-Trihydroxy-3-(p-hydroxyphenyl)propiophenone; Dihydronaringenin; NSC 407292; Naringenin dihydrochalcone; Phloretol; RJC 02792; α,β-Dihydrochalconaringenin; β-(p-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone; β-(p-Hydroxyphenyl)phloropropiophenone |
Structure:
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Related Targets (Total: 10)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T02M5I | Monocarboxylate transporter 1 | SLC16A1 |
P53985 |
A | 1 Reference(s) |
| T42PUG | Solute carrier family 2, facilitated glucose transporter member 1 | SLC2A1 |
P11166 |
A | 4 Reference(s) |
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
A | 3 Reference(s) |
| T34OSI | Solute carrier family 23 member 2 | SLC23A2 |
Q9UGH3 |
A | 1 Reference(s) |
| T64BPL | Solute carrier family 23 member 1 | SLC23A1 |
Q9UHI7 |
A | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
B | 1 Reference(s) |
| T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
B | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
C | 1 Reference(s) |
| T33OSQ | Sterol regulatory element-binding protein 1 | SREBF1 |
P36956 |
C | 1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 8)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0042 | Bai Tou Weng | 白头翁 | Chinese pulsatilla | Pulsatilla chinensis |
| H0120 | Ban Bian Qi | 半边旗 | pinnated brake herb | Pteris semipinnata |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
Ckey description of the interaction between compound and target