Compound Description

ID:   C0484 Common name:   Wedelolactone
IUPAC:  1,8,9-trihydroxy-3-methoxy-[1]benzofuro[3,2-c]chromen-6-one CAS:  CAS:524-12-9
Chembl ID:   CHEMBL97453 Pubchem ID:   CID:5281813
Formula:  C16H10O7 TCM-ID:  TCMC2235
Smiles:  COC1=CC(=C2C(=C1)OC(=O)C3=C2OC4=CC(=C(C=C43)O)O)O
Alias:

1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one;

1,8,9-Trihydroxy-3-methoxy-[1]benzofuro[3,2-c]chromen-6-one;

Wedelolactone
Structure:

Related Targets  (Total: 5)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T20JZ2 Androgen receptorAR P10275
A 1 Reference(s)
T05RAA Inhibitor of nuclear factor kappa-B kinase subunit alphaCHUK O15111
A 1 Reference(s)
T83P5X Inhibitor of nuclear factor kappa-B kinase subunit betaIKBKB O14920
A 1 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
A 3 Reference(s)
T56TXY Polyunsaturated fatty acid 5-lipoxygenaseALOX5 P09917
A 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 4)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1157 Han Lian Cao旱莲草 ecliptaHerba ecliptae prostratae
H0630 Ce Bai Ye侧柏叶 Chinese arborvitae leafThuja orientalis
H0258 Mo Han Lian墨旱莲 YerbadetajoEclipta prostrata
H0625 Ce Bai Tan侧柏炭 Oriental arbor-vitaePlatycladus orientalis