Compound Description
| ID: C0491 | Common name: 1-(4-Hydroxy-Benzyl)-1,2,3,4-Tetrahydro-Isoquinoline-6,7-Diol |
| IUPAC: 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol | CAS: NA |
| Chembl ID: CHEMBL19344 | Pubchem ID: CID:114840 |
| Formula: C16H17NO3 | TCM-ID: TCMC226 |
| Smiles: C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O | |
| Alias:
NA
|
Structure:
|
Related Targets (Total: 5)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
C | 1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
C | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
C | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
C | 1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 15)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0474 | Shu Fu Kuai | 熟附块 | Common monkshood daughter root | Aconitum carmichaeli |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H1062 | Fu Zi | 附子 | Prepared common monkshood daughter root | Aconitum carmichaeli |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0629 | Xi Xin | 细辛 | Siebold wildginger | Asarum sieboldii |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0475 | Shu Fu Pian | 熟附片 | Common monkshood daughter root | Aconitum carmichaeli |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H1063 | Fu Zi Ren | 附子仁 | Prepared common monkshood daughter root | Aconitum carmichaeli |
| H1057 | Fu Pian | 附片 | Common monkshood daughter root | Aconitum carmichaeli |
| H0443 | Sheng Fu Zi | 生附子 | Prepared common monkshood daughter root | Aconitum carmichaeli |
| H0945 | Dan Fu Pian | 淡附片 | NA | Aconitum carmichaeli |
Ckey description of the interaction between compound and target