Compound Description
| ID: C0518 | Common name: Dehydrocostuslactone |
| IUPAC: (3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one | CAS: NA |
| Chembl ID: CHEMBL88985 | Pubchem ID: CID:73174 |
| Formula: C15H18O2 | TCM-ID: TCMC2439 |
| Smiles: C=C1CCC2C(C3C1CCC3=C)OC(=O)C2=C | |
| Alias:
NA
|
Structure:
|
Related Targets (Total: 11)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
A | 1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
B | 1 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
B | 1 Reference(s) |
| T80PUR | Caspase-7 | CASP7 |
P55210 |
B | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
B | 1 Reference(s) |
| T16Q09 | Bcl-2 homologous antagonist/killer | BAK1 |
Q16611 |
C | 1 Reference(s) |
| T49QKE | Bcl-2-interacting killer | BIK |
Q13323 |
C | 1 Reference(s) |
| T58MTG | Bcl-2-related ovarian killer protein | BOK |
Q9UMX3 |
C | 1 Reference(s) |
| T63TJE | Bcl-2-modifying factor | BMF |
Q96LC9 |
C | 1 Reference(s) |
| T74I49 | Bcl-2-like protein 1 | BCL2L1 |
Q07817 |
C | 1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 7)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0610 | Wu Xiang Xue Teng | 五香血藤 | longpeduncle kadsura stem | Schisandra sphenanthera |
| H0876 | Chuan Mu Xiang | 川木香 | Common vladimiria | Vladimiria souliei |
| H0260 | Mo Xiang | 没香 | Myrrh | Commiphora myrrha |
| H0261 | Mo Yao | 没药 | Myrrh | Commiphora myrrha |
| H0274 | Mu Xiang | 木香 | Common aucklandia | Saussurea lappa |
| H0763 | Yu Mi Xu | 玉米须 | Maize style | Zea mays |
| H1126 | Guang Mu Xiang | 广木香 | root of saussurea | Radix aucklandiae |
Ckey description of the interaction between compound and target