Target Description

Type Detail
Target ID T58MTG
Protein Name Bcl-2-related ovarian killer protein
Uniprot ID Q9UMX3
Protein Name Alias hBOK;  Bcl-2-like protein 9;  Bcl2-L-9
Gene ID 666
Gene Symbol BOK
Gene Alias BCL2L9
TTD NA
Pfam PF00452
GO
0005741:mitochondrial outer membrane

0005634:nucleus

0051480:regulation of cytosolic calcium ion concentration

1901030:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

0005640:nuclear outer membrane

0055038:recycling endosome membrane

0008630:intrinsic apoptotic signaling pathway in response to DNA damage

0048709:oligodendrocyte differentiation

0006921:cellular component disassembly involved in execution phase of apoptosis

0031966:mitochondrial membrane

0051400:BH domain binding

0031625:ubiquitin protein ligase binding

0051402:neuron apoptotic process

0016020:membrane

2001244:positive regulation of intrinsic apoptotic signaling pathway

0033106:cis-Golgi network membrane

0043524:negative regulation of neuron apoptotic process

0042803:protein homodimerization activity

0010506:regulation of autophagy

0046982:protein heterodimerization activity

0060546:negative regulation of necroptotic process

1904708:regulation of granulosa cell apoptotic process

0005789:endoplasmic reticulum membrane

0005783:endoplasmic reticulum

0005743:mitochondrial inner membrane

0044877:protein-containing complex binding

0051259:protein complex oligomerization

0016021:integral component of membrane

0032588:trans-Golgi network membrane

1901029:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

0007420:brain development

0001836:release of cytochrome c from mitochondria

1902237:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

0006915:apoptotic process

0097192:extrinsic apoptotic signaling pathway in absence of ligand

0072332:intrinsic apoptotic signaling pathway by p53 class mediator

0008635:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

0008584:male gonad development

1903899:positive regulation of PERK-mediated unfolded protein response

1901382:regulation of chorionic trophoblast cell proliferation

0043065:positive regulation of apoptotic process

0051902:negative regulation of mitochondrial depolarization

1900119:positive regulation of execution phase of apoptosis

0005102:signaling receptor binding

0005794:Golgi apparatus

0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process

0005737:cytoplasm

0031901:early endosome membrane

0005739:mitochondrion

PDB 6CKV
Drugbank NA
KEGG hsa:666

Related Compounds  (Total: 1)

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C0518
Name: Dehydrocostuslactone


Related Herbs  (Total: 7)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0763 Yu Mi Xu玉米须 Maize styleZea mays
H0610 Wu Xiang Xue Teng五香血藤 longpeduncle kadsura stemSchisandra sphenanthera
H0260 Mo Xiang没香 MyrrhCommiphora myrrha
H0876 Chuan Mu Xiang川木香 Common vladimiriaVladimiria souliei
H0274 Mu Xiang木香 Common aucklandiaSaussurea lappa
H1126 Guang Mu Xiang广木香 root of saussureaRadix aucklandiae
H0261 Mo Yao没药 MyrrhCommiphora myrrha