Compound Description

ID:   C0632 Common name:   Loliolide
IUPAC:  (6S,7aR)-6-hydroxy-4,4,7a-trimethyl-6,7-dihydro-5H-1-benzofuran-2-one CAS:  CAS:5989-02-6
Chembl ID:   CHEMBL227113 Pubchem ID:   CID:100332
Formula:  C11H16O3 TCM-ID:  TCMC3374
Smiles:  O[C@@H]1C[C@@]2(C)OC(=O)C=C2C(C1)(C)C
Alias:

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-6-hydroxy-4,4,7a-trimethyl-, (6S-cis)-;

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-6β-hydroxy-4,4,7aβ-trimethyl-;

(6S,7aR)-5,6,7,7a-Tetrahydro-6-hydroxy-4,4,7a-trimethyl-2(4H)-benzofuranone;

(-)-Loliolide;

(6S,7AR)-loliolide;

Calendin;

Caulilide;

Digiprolactone;

Loliolid;

Loliolide;

NSC 289632
Structure:

Related Targets  (Total: 3)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T85U8U Caspase-3CASP3 P42574
C 1 Reference(s)
T23P74 Caspase-9CASP9 P55211
C 1 Reference(s)
T38T1U Caspase-8CASP8 Q14790
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0108 Ku Lian Pi苦楝皮 Chinaberry-tree barkMelia azedarach
H0700 Ya Zhi Cao鸭跖草 Common dayflowerCommelina communis
H0221 Bei Liu Ji Nu北刘寄奴 ‎Diverse wormwood herbHerba artemisiae anomalae