Compound Description

ID:   C0701 Common name:   Phorbol
IUPAC:  (1S,2S,6R,10S,11R,13S,14R,15R)-1,6,13,14-tetrahydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyltetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dien-5-one CAS:  CAS:17673-25-5
Chembl ID:   CHEMBL124518 Pubchem ID:   CID:442070
Formula:  C20H28O6 TCM-ID:  TCMC3871
Smiles:  OCC1=C[C@H]2[C@H]3[C@@](C3(C)C)(O)[C@@H]([C@H]([C@@]2([C@H]2[C@@](C1)(O)C(=O)C(=C2)C)O)C)O
Alias:

5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-, [1aR-(1aα,1bβ,4aβ,7aα,7bα,8α,9β,9aα)]-;

5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-decahydro-4aβ,7bα,9β,9aα-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-, (+)-;

Phorbol;

(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,7a,7b,8,9,9a-Decahydro-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one;

(+)-Phorbol;

4β-Phorbol;

NSC 154778
Structure:

Related Targets  (Total: 3)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T69ZIZ DNA dC->dU-editing enzyme APOBEC-3AAPOBEC3A P31941
C 1 Reference(s)
T19Y64 DNA dC->dU-editing enzyme APOBEC-3BAPOBEC3B Q9UH17
C 1 Reference(s)
T39PME G protein-coupled receptor kinase 4GRK4 P32298
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0869 Ba Dou巴豆 Pu rging crotonCroton tiglium
H0933 Da Ji(1)大蓟 NAHerba cirsii japonici
H0878 Ba Dou Shuang巴豆霜 Defatted croton seed powderCroton tiglium