HIT-result

ID: C0782	Common name: Brefeldin A
IUPAC: (1S,2S,3E,7R,11E,13R,15R)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-one	CAS: CAS:20350-15-6
Chembl ID: NA	Pubchem ID: CID:5352004
Formula: C16H24O4	TCM-ID: TCMC4932
Smiles: O[C@H]1C[C@H]2[C@H](C1)/C=C/CCC[C@H](OC(=O)/C=C/[C@@H]2O)C
Alias: 4H-Cyclopent[f]oxacyclotridecin-4-one, 1,6,7,8,9,11a,12,13,14,14a-decahydro-1,13-dihydroxy-6-methyl-, [1R-(1R,2E,6S,10E,11aS,13S,14aR*)]-; 4H-Cyclopent[f]oxacyclotridecin-4-one, 1,6,7,8,9,11aβ,12,13,14,14aα-decahydro-1β,13α-dihydroxy-6β-methyl-; (1R,2E,6S,10E,11aS,13S,14aR)-1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one; (+)-Brefeldin A; Ascotoxin; Brefeldin; Brefeldin A; Cyanaein; Cyanein; Decumbin; NSC 107456; NSC 244390; NSC 56310; NSC 89671; Nectrolide; Synergisidin	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T78M0B	ADP-ribosylation factor 1	ARF1	P84077	A	1 Reference(s)
T38S56	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1	GBF1	Q92538	A	1 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	A	1 Reference(s)
T65R2B	Rap guanine nucleotide exchange factor 3	RAPGEF3	O95398	A	4 Reference(s)
T81E9Z	Protein Bop	RTL10	Q7L3V2	A	1 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	C	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis

Compound Description

Related Targets (Total: 6)

Related Herbs (Total: 1)