Compound Description
| ID: C0872 | Common name: Allicin |
| IUPAC: 3-prop-2-enylsulfinylsulfanylprop-1-ene | CAS: CAS:539-86-6 |
| Chembl ID: CHEMBL359965 | Pubchem ID: CID:65036 |
| Formula: C6H10OS2 | TCM-ID: TCMC656 |
| Smiles: C=CCSS(=O)CC=C | |
| Alias:
2-Propene-1-sulfinic acid, thio-, S-allyl ester;
2-Propene-1-sulfinothioic acid, S-2-propenyl ester; Allicin; Allimed; Alliosan; Allisure Liquid; Diallyl thiosulfinate; Dianyctrsnlgide; Thio-2-propene-1-sulfinic acid S-allyl ester |
Structure:
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Related Targets (Total: 14)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
A | 1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
A | 1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
A | 1 Reference(s) |
| T64T4I | Telomerase protein component 1 | TEP1 |
Q99973 |
B | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
B | 2 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
B | 3 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
B | 1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
B | 1 Reference(s) |
| T06KGA | Integrin alpha-4 | ITGA4 |
P13612 |
C | 1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
C | 1 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
C | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
C | 1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
C | 1 Reference(s) |
| T09KQF | Proliferating cell nuclear antigen | PCNA |
P12004 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 6)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0914 | Cong | 葱 | Allium bulb, wild scallion, chinese green onion | Bulbus allii fistulosi |
| H0915 | Cong Bai | 葱白 | Fistular onion | Allium fistulosum |
| H0916 | Cong Tou | 葱头 | Allium bulb, wild scallion, chinese green onion | Bulbus allii fistulosi |
| H0669 | Xie Bai | 薤白 | Longstamen onion | Allium macrostemon |
| H0938 | Da Suan | 大蒜 | Garlic | Allium sativum |
| H0499 | Si Ji Cong Tou | 四季葱头 | Allium bulb, wild scallion, chinese green onion | Bulbus allii fistulosi |
Ckey description of the interaction between compound and target