HIT-result

ID: C0877	Common name: Madecassoside
IUPAC: [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate	CAS: CAS:34540-22-2
Chembl ID: NA	Pubchem ID: CID:24825675
Formula: C48H78O20	TCM-ID: TCMC6610
Smiles: OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC(=O)[C@@]34CC[C@H]([C@@H]([C@H]4C4=CC[C@H]5[C@@]([C@@]4(CC3)C)(C)C[C@@H](O)[C@@H]3[C@]5(C)C[C@H]([C@@H]([C@@]3(C)CO)O)O)C)C)[C@@H]([C@H]([C@@H]2O)O)O)[C@@H]([C@H]([C@@H]1O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O)O)O
Alias: Madecassoside; Asiaticoside A; Redermic	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T31U13	Cytochrome P450 2C19	CYP2C19	P33261	A	1 Reference(s)
T85AXP	Cytochrome P450 3A4	CYP3A4	P08684	A	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	C	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	C	1 Reference(s)
T45X9Z	Hepatocyte growth factor	HGF	P14210	C	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica

Compound Description

Related Targets (Total: 5)

Related Herbs (Total: 1)