Compound Description
| ID: C0887 | Common name: Alprostadil |
| IUPAC: 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid | CAS: CAS:745-65-3 |
| Chembl ID: CHEMBL495 | Pubchem ID: CID:5280723 |
| Formula: C20H34O5 | TCM-ID: TCMC678 |
| Smiles: CCCCC[C@@H](/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O)O | |
| Alias:
Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, (-)-;
Cyclopentaneheptanoic acid, 3α-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-; (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid; (-)-Prostaglandin E1; 11α,15(S)-Dihydroxy-9-oxo-13-trans-prostenoic acid; 11α,15α-Dihydroxy-9-oxo-13-trans-prostenoic acid; Alprostadil; Alprostan; Alprox TD; Caveject; Caverject; Eglandin; Liple; Lipo PGE1; Lipoprost; Liprostin; Minprog; NSC 165559; ONO 1608; PGE1; Palux; Prostaglandin E1; Prostandin; Prostandin 500; Prostin VR Pediatric; Prostivas; SEPA-PGE1; SEPA-alprostadil; SEPA-prostaglandin E1; Topiglan; U 10136; Vasaprostan; l-PGE1; l-Prostaglandin E1 |
Structure:
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Related Targets (Total: 4)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T47DYR | P2Y purinoceptor 1 | P2RY1 |
P47900 |
B | 1 Reference(s) |
| T75PC7 | NA | MIR21 |
NA |
C | 1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
C | 1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 2)
Ckey description of the interaction between compound and target