Compound Description
| ID: C1175 | Common name: Bergenin |
| IUPAC: (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one | CAS: CAS:477-90-7 |
| Chembl ID: CHEMBL273019 | Pubchem ID: CID:66065 |
| Formula: C14H16O9 | TCM-ID: TCMC789 |
| Smiles: OC[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]1O)O)OC(=O)c1c2c(O)c(c(c1)O)OC | |
| Alias:
Bergenin;
Pyrano[3,2-c][2]benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-, [2R-(2α,3β,4α,4aα,10bβ)]-; α-Resorcylic acid, 4-methoxy-2-[tetrahydro-3,4,5-trihydroxy-6-(hydroxymethyl)pyran-2-yl]-, δ-lactone; (2R,3S,4S,4aR,10bS)-3,4,4a,10b-Tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxypyrano[3,2-c][2]benzopyran-6(2H)-one; (-)-Bergenin; Ai Cha Su; Ardisic acid B; Bengenin; Bergeninum; Bergenit; Corylopsin; Cuscutin; NSC 661749; Peltophorin; Vakerin |
Structure:
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Related Targets (Total: 6)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
A | 1 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
A | 1 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
A | 1 Reference(s) |
| T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
A | 1 Reference(s) |
| T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
A | 1 Reference(s) |
| T93O6K | F-box/WD repeat-containing protein 1A | BTRC |
Q9Y297 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 7)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0832 | Zhu Sha Gen | 朱砂根 | Coral ardisia | Ardisia crenata |
| H1201 | Hu Er Cao | 虎耳草 | Creeping rockfoil | Saxifraga stolonifera |
| H0185 | Luo Shi Teng | 络石藤 | Chinese star jasmine | Trachelospermum jasminoides |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H0848 | Zi Jin Niu | 紫金牛 | Japanese ardisia | Ardisia japonica |
Ckey description of the interaction between compound and target