HIT-result

Type	Detail
Target ID	T93O6K
Protein Name	F-box/WD repeat-containing protein 1A
Uniprot ID	Q9Y297
Protein Name Alias	E3RSIkappaB; Epididymis tissue protein Li 2a; F-box and WD repeats protein beta-TrCP; pIkappaBalpha-E3 receptor subunit
Gene ID	8945
Gene Symbol	BTRC
Gene Alias	BTRCP; FBW1A; FBXW1A
TTD	NA
Pfam	PF12125 ; PF00400 ; PF12937
GO	0016567:protein ubiquitination 0070498:interleukin-1-mediated signaling pathway 0045309:protein phosphorylated amino acid binding 1901990:regulation of mitotic cell cycle phase transition 0019005:SCF ubiquitin ligase complex 0070936:protein K48-linked ubiquitination 0042752:regulation of circadian rhythm 0016874:ligase activity 0006470:protein dephosphorylation 0002223:stimulatory C-type lectin receptor signaling pathway 0060444:branching involved in mammary gland duct morphogenesis 0045892:negative regulation of transcription, DNA-templated 0043687:post-translational protein modification 0050852:T cell receptor signaling pathway 0045879:negative regulation of smoothened signaling pathway 0071407:cellular response to organic cyclic compound 0043161:proteasome-mediated ubiquitin-dependent protein catabolic process 0042753:positive regulation of circadian rhythm 0006511:ubiquitin-dependent protein catabolic process 0043122:regulation of I-kappaB kinase/NF-kappaB signaling 0038095:Fc-epsilon receptor signaling pathway 0005829:cytosol 0031648:protein destabilization 1990756:ubiquitin ligase-substrate adaptor activity 0060828:regulation of canonical Wnt signaling pathway 0016055:Wnt signaling pathway 0038061:NIK/NF-kappaB signaling 0048511:rhythmic process 0046983:protein dimerization activity 0000209:protein polyubiquitination 0051403:stress-activated MAPK cascade 0045862:positive regulation of proteolysis 0045893:positive regulation of transcription, DNA-templated 0031146:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0043433:negative regulation of DNA-binding transcription factor activity 0007165:signal transduction 1990757:ubiquitin ligase activator activity 0016032:viral process 0000086:G2/M transition of mitotic cell cycle 0005654:nucleoplasm 1904668:positive regulation of ubiquitin protein ligase activity 0061136:regulation of proteasomal protein catabolic process 0061630:ubiquitin protein ligase activity 0008013:beta-catenin binding 0033598:mammary gland epithelial cell proliferation
PDB	2P64 ; 6M90 ; 6TTU ; 6M94 ; 6M91 ; 6M93 ; 1P22 ; 6M92
Drugbank	NA
KEGG	hsa:8945

Go to browser

Name: Bergenin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1201	Hu Er Cao	虎耳草	Creeping rockfoil	Saxifraga stolonifera
H1016	Du Zhong Tan	杜仲炭	Eucommia	Eucommia ulmoides
H0185	Luo Shi Teng	络石藤	Chinese star jasmine	Trachelospermum jasminoides
H0832	Zhu Sha Gen	朱砂根	Coral ardisia	Ardisia crenata
H1017	Du Zhong Ye	杜仲叶	Eucommia leaf	Eucommia ulmoides
H0848	Zi Jin Niu	紫金牛	Japanese ardisia	Ardisia japonica
H1015	Du Zhong	杜仲	Eucommia	Eucommia ulmoides