Compound Description
| ID: C1252 | Common name: Corilagin |
| IUPAC: NA | CAS: CAS:23094-69-1 |
| Chembl ID: CHEMBL449392 | Pubchem ID: CID:73568 |
| Formula: C27H22O18 | TCM-ID: TCMC941 |
| Smiles: C1C2C(C(C(C(O2)OC(=O)C3=CC(=C(C(=C3)O)O)O)O)OC(=O)C4=CC(=C(C(=C4C5=C(C(=C(C=C5C(=O)O1)O)O)O)O)O)O)O | |
| Alias:
Corilagin;
Glucopyranose, cyclic 3,6-(4,4',5,5',6,6'-hexahydroxydiphenate) 1-gallate, β-D-; β-D-Glucopyranose, cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), (R)-; 8,12-Methano-10H-dibenzo[j,l][1,4,8]trioxacyclotetradecin, β-D-glucopyranose deriv.; Corillagin |
Structure:
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Related Targets (Total: 16)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
A | 1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
A | 3 Reference(s) |
| T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
A | 1 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
A | 1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
A | 1 Reference(s) |
| T98FWP | NF-kappa-B essential modulator | IKBKG |
Q9Y6K9 |
A | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
B | 1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
B | 1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
B | 1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
B | 1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
B | 1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
B | 1 Reference(s) |
| T16FZA | Prolyl endopeptidase | PREP |
P48147 |
B | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
C | 1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
C | 1 Reference(s) |
| T24YNT | E3 ubiquitin-protein ligase RNF8 | RNF8 |
O76064 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 16)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0569 | Tu Er San | 兔儿伞 | Syneilesis* | Syneilesis palmata |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H1170 | He Zi | 诃子 | Medicine terminalia | Terminalia chebula |
| H1137 | Gui Yuan | 桂圆 | NA | Dimocarpus longan |
| H0547 | Cang Qing Guo | 藏青果 | Myrobalan | Terminalia chebula |
| H0974 | Di Jin Cao | 地锦草 | Humifuse euphorbia | Euphorbia humifusa |
| H0975 | Di Mian Cao | 地绵草 | NA | Euphorbia humifusa |
| H1082 | Gan Lan | 橄榄 | Cabbage | Canarium album |
| H0344 | Qing Guo | 青果 | Olive | Canarium album |
| H0060 | Jin Si Ku Lian | 金丝苦楝 | NA | Cardiospermum halicacabum |
| H0128 | Lao Guan Cao | 老鹳草 | Wilford cranesbill | Geranium wilfordii |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0345 | Qing Guo Tan | 青果炭 | white olive | Canarium album |
| H1171 | He Zi Rou | 诃子肉 | Medicine terminalia | Terminalia chebula |
Ckey description of the interaction between compound and target