HIT-result

Type	Detail
Target ID	T03H54
Protein Name	Protein Mdm4
Uniprot ID	O15151
Protein Name Alias	Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4
Gene ID	4194
Gene Symbol	MDM4
Gene Alias	MDMX
TTD	T36741: Clinical Trial target
Pfam	PF00641 ; PF02201
GO	0005634:nucleus 0003170:heart valve development 0071456:cellular response to hypoxia 0005654:nucleoplasm 0006977:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 0003203:endocardial cushion morphogenesis 0008285:negative regulation of cell population proliferation 0065003:protein-containing complex assembly 1901796:regulation of signal transduction by p53 class mediator 0003181:atrioventricular valve morphogenesis 0019899:enzyme binding 0003281:ventricular septum development 0030330:DNA damage response, signal transduction by p53 class mediator 0042177:negative regulation of protein catabolic process 0050821:protein stabilization 0003283:atrial septum development 0000122:negative regulation of transcription by RNA polymerase II 0008270:zinc ion binding 0071157:negative regulation of cell cycle arrest 0006357:regulation of transcription by RNA polymerase II 0016579:protein deubiquitination 0045944:positive regulation of transcription by RNA polymerase II 0043066:negative regulation of apoptotic process
PDB	2N14 ; 7C3Q ; 5UML ; 6Q9W ; 3FE7 ; 3JZP ; 2N0W ; 3LBJ ; 3FEA ; 6Q9Q ; 7C3Y ; 2VJE ; 3JZO ; 2N06 ; 2VJF ; 6Q9S ; 2CR8 ; 3DAB ; 2MWY ; 5VK1 ; 2N0U ; 3EQY ; 3U15 ; 6Q9U ; 2VYR ; 4RXZ ; 5MNJ ; 6Q9Y ; 7C44 ; 3FDO ; 3JZQ ; 3MQR
Drugbank	NA
KEGG	hsa:4194

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Name: Lithocholic Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0488	Shui Niu Jiao Gan Jin Gao	水牛角干浸膏	Buffalo horn	Bubalus bubalis
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0292	Niu Jiao Jian Fen	牛角尖粉	Buffalo horn	Bubalus bubalis
H0487	Shui Niu Jiao	水牛角	Buffalo horn	Bubalus bubalis
H0489	Shui Niu Jiao Nong Suo Fen	水牛角浓缩粉	Buffalo horn	Bubalus bubalis
H0291	Niu Jiao Fen	牛角粉	Buffalo horn	Bubalus bubalis
H0293	Niu Jiao Tan	牛角炭	Buffalo horn	Bubalus bubalis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens