Compound Description

ID:   C0194 Common name:   Lithocholic Acid
IUPAC:  (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid CAS:  CAS:434-13-9
Chembl ID:   CHEMBL1478 Pubchem ID:   CID:9903
Formula:  C24H40O3 TCM-ID:  TCMC1504
Smiles:  O[C@@H]1CC[C@]2([C@@H](C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)O)C)C)C
Alias:

5β-Cholan-24-oic acid, 3α-hydroxy-;

5β-Cholanic acid, 3α-hydroxy-;

(3α,5β)-3-Hydroxycholan-24-oic acid;

17β-(1-Methyl-3-carboxypropyl)etiocholan-3α-ol;

3-Hydroxycholan-24-oic acid;

3α-Hydroxy-5β-cholan-24-oate;

3α-Hydroxy-5β-cholan-24-oic acid;

3α-Hydroxy-5β-cholanic acid;

3α-Hydroxy-5β-cholanoic acid;

3α-Hydroxycholanic acid;

Lithocholic acid;

NSC 683770
Structure:

Related Targets  (Total: 8)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T50SX0 Nuclear receptor subfamily 1 group I member 2NR1I2 O75469
A 2 Reference(s)
T74P7I G-protein coupled bile acid receptor 1GPBAR1 Q8TDU6
A 2 Reference(s)
T78GRC Aldo-keto reductase family 1 member C3AKR1C3 P42330
A 1 Reference(s)
T24C0P Bile acid receptorNR1H4 Q96RI1
A 1 Reference(s)
T03H54 Protein Mdm4MDM4 O15151
A 1 Reference(s)
T23IBY DNA polymerase betaPOLB P06746
A 1 Reference(s)
T06PVX E3 ubiquitin-protein ligase Mdm2MDM2 Q00987
A 1 Reference(s)
T60A9R NACYP3A NA
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 8)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0488 Shui Niu Jiao Gan Jin Gao水牛角干浸膏 Buffalo hornBubalus bubalis
H0489 Shui Niu Jiao Nong Suo Fen水牛角浓缩粉 Buffalo hornBubalus bubalis
H0487 Shui Niu Jiao水牛角 Buffalo hornBubalus bubalis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0293 Niu Jiao Tan牛角炭 Buffalo hornBubalus bubalis
H0292 Niu Jiao Jian Fen牛角尖粉 Buffalo hornBubalus bubalis
H0291 Niu Jiao Fen牛角粉 Buffalo hornBubalus bubalis