HIT-result

Type	Detail
Target ID	T03OGP
Protein Name	CCN family member 1
Uniprot ID	O00622
Protein Name Alias	Cellular communication network factor 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10; IBP-10; IGF-binding protein 10; IGFBP-10; Protein CYR61; Protein GIG1
Gene ID	3491
Gene Symbol	CCN1
Gene Alias	CYR61; GIG1; IGFBP10
TTD	T56505: Research target
Pfam	PF00219 ; PF19035 ; PF00093 ; PF00007
GO	0030513:positive regulation of BMP signaling pathway 0061036:positive regulation of cartilage development 0007155:cell adhesion 0045860:positive regulation of protein kinase activity 0030335:positive regulation of cell migration 0060716:labyrinthine layer blood vessel development 0043280:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 0044267:cellular protein metabolic process 0003278:apoptotic process involved in heart morphogenesis 0060710:chorio-allantoic fusion 0060548:negative regulation of cell death 0033690:positive regulation of osteoblast proliferation 0060591:chondroblast differentiation 0030198:extracellular matrix organization 0003181:atrioventricular valve morphogenesis 0008201:heparin binding 0001934:positive regulation of protein phosphorylation 0030501:positive regulation of bone mineralization 0031012:extracellular matrix 0070372:regulation of ERK1 and ERK2 cascade 0060413:atrial septum morphogenesis 0003281:ventricular septum development 2000304:positive regulation of ceramide biosynthetic process 0001649:osteoblast differentiation 0005178:integrin binding 0010811:positive regulation of cell-substrate adhesion 0002041:intussusceptive angiogenesis 0062023:collagen-containing extracellular matrix 0045669:positive regulation of osteoblast differentiation 0043065:positive regulation of apoptotic process 0005576:extracellular region 0010518:positive regulation of phospholipase activity 0044319:wound healing, spreading of cells 0007165:signal transduction 0005520:insulin-like growth factor binding 0072593:reactive oxygen species metabolic process 0006935:chemotaxis 0050840:extracellular matrix binding 0045944:positive regulation of transcription by RNA polymerase II 0043687:post-translational protein modification 0043066:negative regulation of apoptotic process 0005788:endoplasmic reticulum lumen
PDB	4D11 ; 4D0Z
Drugbank	NA
KEGG	hsa:3491

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Name: Cycloheximide

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1202	Hu Huang Lian	胡黄连	Picrorhiza	Picrorhiza kurrooa
H0320	Qi Shu Gen	漆树根	true lacquertree root	Toxicodendron succedaneum