Compound Description

ID:   C1271 Common name:   Cycloheximide
IUPAC:  4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione CAS:  CAS:66-81-9
Chembl ID:   CHEMBL123292 Pubchem ID:   CID:6197
Formula:  C15H23NO4 TCM-ID:  TCMC969
Smiles:  C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@@H](CC1CC(=NC(=O)C1)O)O
Alias:

2,6-Piperidinedione, 4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-, [1S-[1α(S*),3α,5β]]-;

Glutarimide, 3-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-;

Naramycin A;

4-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-2,6-piperidinedione;

(-)-Cycloheximide;

3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide;

Acti-Aid;

Acti-dione;

Acti-dione BR;

Acti-dione PM;

Acti-dione TGF;

Actidion;

CHX;

Cicloheximide;

Cycloheximide;

FT 3422-2;

LDN 97549;

NM-MCD 80;

NSC 185;

Naramycin;

Naramycin Microcapsule D 80;

Naramycin NM-MCU 80;

TZA;

U 4527;

l-Cycloheximide;

β-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide
Structure:

Related Targets  (Total: 11)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T26KIE Transcription factor AP-1JUN P05412
A 1 Reference(s)
T68OIU CREB-regulated transcription coactivator 1CRTC1 Q6UUV9
A 1 Reference(s)
T03OGP CCN family member 1CCN1 O00622
A 1 Reference(s)
T29MD1 Mitogen-activated protein kinase 8MAPK8 P45983
A 1 Reference(s)
T93VFT Endothelin-1EDN1 P05305
A 1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
C 1 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
C 1 Reference(s)
T42K6K M-phase inducer phosphatase 3CDC25C P30307
C 1 Reference(s)
T40SWE Glutamate carboxypeptidase 2FOLH1 Q04609
C 1 Reference(s)
T86ROZ Heme oxygenase 1HMOX1 P09601
C 1 Reference(s)
T25NV9 TAR DNA-binding protein 43TARDBP Q13148
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1202 Hu Huang Lian胡黄连 PicrorhizaPicrorhiza kurrooa
H0320 Qi Shu Gen漆树根 true lacquertree rootToxicodendron succedaneum