Target Description

Type Detail
Target ID T25NV9
Protein Name TAR DNA-binding protein 43
Uniprot ID Q13148
Protein Name Alias TDP-43
Gene ID 23435
Gene Symbol TARDBP
Gene Alias TDP43
TTD T08014: Clinical Trial target
Pfam PF00076 ; PF18694
0042802:identical protein binding


0034976:response to endoplasmic reticulum stress

0042981:regulation of apoptotic process

0097157:pre-mRNA intronic binding

0032024:positive regulation of insulin secretion

0008380:RNA splicing

0035061:interchromatin granule

0042752:regulation of circadian rhythm

0010468:regulation of gene expression

0003730:mRNA 3'-UTR binding

0042307:positive regulation of protein import into nucleus

0006397:mRNA processing

0043922:negative regulation by host of viral transcription

0001933:negative regulation of protein phosphorylation

0010629:negative regulation of gene expression

0048511:rhythmic process

0005726:perichromatin fibrils

0003723:RNA binding

0003690:double-stranded DNA binding

0010494:cytoplasmic stress granule

0070935:3'-UTR-mediated mRNA stabilization

0061158:3'-UTR-mediated mRNA destabilization

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding


0051726:regulation of cell cycle

0031647:regulation of protein stability

0016607:nuclear speck

0071765:nuclear inner membrane organization

PDB 2N2C ; 6T4B ; 5WHN ; 5W7V ; 2N4P ; 5WKB ; 4BS2 ; 2CQG ; 1WF0 ; 5MRG ; 5WKD ; 6N3A ; 6B1G ; 4Y00 ; 2N4H ; 5WIA ; 5X4F ; 4Y0F ; 6CFH ; 5MDI ; 5W52 ; 5WHP ; 6N3C ; 4IUF ; 2N4G ; 5WIQ ; 6CF4 ; 2N3X ; 6N37 ; 5W50 ; 6N3B
Drugbank NA
KEGG hsa:23435

Related Compounds  (Total: 1)

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Name: Cycloheximide

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0320 Qi Shu Gen漆树根 true lacquertree rootToxicodendron succedaneum
H1202 Hu Huang Lian胡黄连 PicrorhizaPicrorhiza kurrooa