HIT-result

Type	Detail
Target ID	T25NV9
Protein Name	TAR DNA-binding protein 43
Uniprot ID	Q13148
Protein Name Alias	TDP-43
Gene ID	23435
Gene Symbol	TARDBP
Gene Alias	TDP43
TTD	T08014: Clinical Trial target
Pfam	PF00076 ; PF18694
GO	0042802:identical protein binding 0005634:nucleus 0034976:response to endoplasmic reticulum stress 0042981:regulation of apoptotic process 0097157:pre-mRNA intronic binding 0032024:positive regulation of insulin secretion 0008380:RNA splicing 0035061:interchromatin granule 0042752:regulation of circadian rhythm 0010468:regulation of gene expression 0003730:mRNA 3'-UTR binding 0042307:positive regulation of protein import into nucleus 0006397:mRNA processing 0043922:negative regulation by host of viral transcription 0001933:negative regulation of protein phosphorylation 0010629:negative regulation of gene expression 0048511:rhythmic process 0005726:perichromatin fibrils 0003723:RNA binding 0003690:double-stranded DNA binding 0010494:cytoplasmic stress granule 0070935:3'-UTR-mediated mRNA stabilization 0061158:3'-UTR-mediated mRNA destabilization 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0005654:nucleoplasm 0051726:regulation of cell cycle 0031647:regulation of protein stability 0016607:nuclear speck 0071765:nuclear inner membrane organization
PDB	2N2C ; 6T4B ; 5WHN ; 5W7V ; 2N4P ; 5WKB ; 4BS2 ; 2CQG ; 1WF0 ; 5MRG ; 5WKD ; 6N3A ; 6B1G ; 4Y00 ; 2N4H ; 5WIA ; 5X4F ; 4Y0F ; 6CFH ; 5MDI ; 5W52 ; 5WHP ; 6N3C ; 4IUF ; 2N4G ; 5WIQ ; 6CF4 ; 2N3X ; 6N37 ; 5W50 ; 6N3B
Drugbank	NA
KEGG	hsa:23435

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Name: Cycloheximide

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1202	Hu Huang Lian	胡黄连	Picrorhiza	Picrorhiza kurrooa
H0320	Qi Shu Gen	漆树根	true lacquertree root	Toxicodendron succedaneum