HIT-result

Type	Detail
Target ID	T04SA9
Protein Name	Delta(24)-sterol reductase
Uniprot ID	Q15392
Protein Name Alias	EC 1.3.1.72; 24-dehydrocholesterol reductase; 3-beta-hydroxysterol Delta-24-reductase; Diminuto/dwarf1 homolog; Seladin-1
Gene ID	1718
Gene Symbol	DHCR24
Gene Alias	KIAA0018
TTD	T90935: Research target
Pfam	PF01565
GO	0005634:nucleus 0050614:delta24-sterol reductase activity 0007050:cell cycle arrest 0008202:steroid metabolic process 0005789:endoplasmic reticulum membrane 0033489:cholesterol biosynthetic process via desmosterol 0042605:peptide antigen binding 0009888:tissue development 0033490:cholesterol biosynthetic process via lathosterol 0006915:apoptotic process 0000246:delta24(24-1) sterol reductase activity 0000139:Golgi membrane 0005783:endoplasmic reticulum 0019899:enzyme binding 0016021:integral component of membrane 0016628:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 0016020:membrane 0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0006979:response to oxidative stress 0005737:cytoplasm 0006695:cholesterol biosynthetic process 0043588:skin development 0043066:negative regulation of apoptotic process 1901214:regulation of neuron death 0071949:FAD binding
PDB	NA
Drugbank	NA
KEGG	hsa:1718

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description