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Target Description
Type
Detail
Target ID
T06DT8
Protein Name
Roundabout homolog 1
Uniprot ID
Q9Y6N7
Protein Name Alias
Deleted in U twenty twenty; H-Robo-1
Gene ID
6091
Gene Symbol
ROBO1
Gene Alias
DUTT1
TTD
T72944: Research target
Pfam
PF00041
;
PF07679
GO
0007399:nervous system development
0010629:negative regulation of gene expression
0009986:cell surface
0030424:axon
0050925:negative regulation of negative chemotaxis
0035481:positive regulation of Notch signaling pathway involved in heart induction
0003272:endocardial cushion formation
0007156:homophilic cell adhesion via plasma membrane adhesion molecules
0002042:cell migration involved in sprouting angiogenesis
0030275:LRR domain binding
0030336:negative regulation of cell migration
0033116:endoplasmic reticulum-Golgi intermediate compartment membrane
0008046:axon guidance receptor activity
0042802:identical protein binding
0035385:Roundabout signaling pathway
0070100:negative regulation of chemokine-mediated signaling pathway
0003184:pulmonary valve morphogenesis
0035025:positive regulation of Rho protein signal transduction
0005886:plasma membrane
0005887:integral component of plasma membrane
0005737:cytoplasm
0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process
0035904:aorta development
0060412:ventricular septum morphogenesis
0050772:positive regulation of axonogenesis
0007411:axon guidance
0010628:positive regulation of gene expression
0003148:outflow tract septum morphogenesis
0043406:positive regulation of MAP kinase activity
0033600:negative regulation of mammary gland epithelial cell proliferation
0016199:axon midline choice point recognition
0007155:cell adhesion
0021836:chemorepulsion involved in postnatal olfactory bulb interneuron migration
0003180:aortic valve morphogenesis
1900748:positive regulation of vascular endothelial growth factor signaling pathway
PDB
2V9Q
;
2V9R
;
5OPE
;
5O5I
;
6A79
;
2V9T
;
2EO9
;
3WIH
;
4HLJ
;
6A77
;
6A78
;
5O5G
Drugbank
NA
KEGG
hsa:6091
Related Compounds (Total: 1)
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C1113
Name: heparin
Related Herbs (Total: 0)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name