Target Description

Type Detail
Target ID T06DT8
Protein Name Roundabout homolog 1
Uniprot ID Q9Y6N7
Protein Name Alias Deleted in U twenty twenty;  H-Robo-1
Gene ID 6091
Gene Symbol ROBO1
Gene Alias DUTT1
TTD T72944: Research target
Pfam PF00041 ; PF07679
GO
0007399:nervous system development

0010629:negative regulation of gene expression

0009986:cell surface

0030424:axon

0050925:negative regulation of negative chemotaxis

0035481:positive regulation of Notch signaling pathway involved in heart induction

0003272:endocardial cushion formation

0007156:homophilic cell adhesion via plasma membrane adhesion molecules

0002042:cell migration involved in sprouting angiogenesis

0030275:LRR domain binding

0030336:negative regulation of cell migration

0033116:endoplasmic reticulum-Golgi intermediate compartment membrane

0008046:axon guidance receptor activity

0042802:identical protein binding

0035385:Roundabout signaling pathway

0070100:negative regulation of chemokine-mediated signaling pathway

0003184:pulmonary valve morphogenesis

0035025:positive regulation of Rho protein signal transduction

0005886:plasma membrane

0005887:integral component of plasma membrane

0005737:cytoplasm

0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process

0035904:aorta development

0060412:ventricular septum morphogenesis

0050772:positive regulation of axonogenesis

0007411:axon guidance

0010628:positive regulation of gene expression

0003148:outflow tract septum morphogenesis

0043406:positive regulation of MAP kinase activity

0033600:negative regulation of mammary gland epithelial cell proliferation

0016199:axon midline choice point recognition

0007155:cell adhesion

0021836:chemorepulsion involved in postnatal olfactory bulb interneuron migration

0003180:aortic valve morphogenesis

1900748:positive regulation of vascular endothelial growth factor signaling pathway

PDB 2V9Q ; 2V9R ; 5OPE ; 5O5I ; 6A79 ; 2V9T ; 2EO9 ; 3WIH ; 4HLJ ; 6A77 ; 6A78 ; 5O5G
Drugbank NA
KEGG hsa:6091

Related Compounds  (Total: 1)

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C1113
Name: heparin


Related Herbs  (Total: 0)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name