HIT-result

Type	Detail
Target ID	T06HS2
Protein Name	Tumor necrosis factor receptor superfamily member 11A
Uniprot ID	Q9Y6Q6
Protein Name Alias	Osteoclast differentiation factor receptor; ODFR; Receptor activator of NF-KB; CD antigen CD265
Gene ID	8792
Gene Symbol	TNFRSF11A
Gene Alias	RANK
TTD	T85746: Research target
Pfam	PF00020 ; PF18278
GO	0002548:monocyte chemotaxis 0005829:cytosol 0005031:tumor necrosis factor-activated receptor activity 0048535:lymph node development 0046872:metal ion binding 0051091:positive regulation of DNA-binding transcription factor activity 0002250:adaptive immune response 0034097:response to cytokine 0034612:response to tumor necrosis factor 0045780:positive regulation of bone resorption 0009897:external side of plasma membrane 0032496:response to lipopolysaccharide 0070555:response to interleukin-1 0072674:multinuclear osteoclast differentiation 0009314:response to radiation 0071847:TNFSF11-mediated signaling pathway 0007165:signal transduction 0060086:circadian temperature homeostasis 0016021:integral component of membrane 0043507:positive regulation of JUN kinase activity 0071848:positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling 0005886:plasma membrane 0051092:positive regulation of NF-kappaB transcription factor activity 0038023:signaling receptor activity 0033209:tumor necrosis factor-mediated signaling pathway 0008284:positive regulation of cell population proliferation 0030316:osteoclast differentiation 0007267:cell-cell signaling 0019955:cytokine binding 0004888:transmembrane signaling receptor activity 0001503:ossification 0060749:mammary gland alveolus development 0071812:positive regulation of fever generation by positive regulation of prostaglandin secretion
PDB	1LB5
Drugbank	DB05959
KEGG	hsa:8792

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Name: (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens