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Target Description
Type
Detail
Target ID
T08THQ
Protein Name
Phosphatidylcholine translocator ABCB4
Uniprot ID
P21439
Protein Name Alias
EC 7.6.2.1; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3
Gene ID
5244
Gene Symbol
ABCB4
Gene Alias
MDR3; PGY3
TTD
T93062: Clinical Trial target
Pfam
PF00005
;
PF00664
GO
0061092:positive regulation of phospholipid translocation
0005654:nucleoplasm
2001140:positive regulation of phospholipid transport
0016887:ATPase activity
0016020:membrane
0045332:phospholipid translocation
0006629:lipid metabolic process
0005886:plasma membrane
0055088:lipid homeostasis
0005829:cytosol
0070062:extracellular exosome
0005925:focal adhesion
0015629:actin cytoskeleton
0016021:integral component of membrane
0032376:positive regulation of cholesterol transport
0005524:ATP binding
0099040:ceramide translocation
0030136:clathrin-coated vesicle
0042910:xenobiotic transmembrane transporter activity
0019222:regulation of metabolic process
0045121:membrane raft
0046581:intercellular canaliculus
0042626:ATPase-coupled transmembrane transporter activity
0090555:phosphatidylethanolamine flippase activity
1903413:cellular response to bile acid
0032782:bile acid secretion
0090554:phosphatidylcholine floppase activity
1901557:response to fenofibrate
0005887:integral component of plasma membrane
0005737:cytoplasm
0016324:apical plasma membrane
0055085:transmembrane transport
PDB
6S7P
Drugbank
DB06414
;
DB06207
KEGG
hsa:5244
Related Compounds (Total: 1)
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C1228
Name: Chenodiol
Related Herbs (Total: 2)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens