Target Description

Type Detail
Target ID T08THQ
Protein Name Phosphatidylcholine translocator ABCB4
Uniprot ID P21439
Protein Name Alias EC 7.6.2.1;  ATP-binding cassette sub-family B member 4;  Multidrug resistance protein 3;  P-glycoprotein 3
Gene ID 5244
Gene Symbol ABCB4
Gene Alias MDR3;  PGY3
TTD T93062: Clinical Trial target
Pfam PF00005 ; PF00664
GO
0061092:positive regulation of phospholipid translocation

0005654:nucleoplasm

2001140:positive regulation of phospholipid transport

0016887:ATPase activity

0016020:membrane

0045332:phospholipid translocation

0006629:lipid metabolic process

0005886:plasma membrane

0055088:lipid homeostasis

0005829:cytosol

0070062:extracellular exosome

0005925:focal adhesion

0015629:actin cytoskeleton

0016021:integral component of membrane

0032376:positive regulation of cholesterol transport

0005524:ATP binding

0099040:ceramide translocation

0030136:clathrin-coated vesicle

0042910:xenobiotic transmembrane transporter activity

0019222:regulation of metabolic process

0045121:membrane raft

0046581:intercellular canaliculus

0042626:ATPase-coupled transmembrane transporter activity

0090555:phosphatidylethanolamine flippase activity

1903413:cellular response to bile acid

0032782:bile acid secretion

0090554:phosphatidylcholine floppase activity

1901557:response to fenofibrate

0005887:integral component of plasma membrane

0005737:cytoplasm

0016324:apical plasma membrane

0055085:transmembrane transport

PDB 6S7P
Drugbank DB06414 ; DB06207
KEGG hsa:5244

Related Compounds  (Total: 1)

Go to browser
C1228
Name: Chenodiol


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens