HIT-result

Type	Detail
Target ID	T09K8S
Protein Name	Protein arginine N-methyltransferase 1
Uniprot ID	Q99873
Protein Name Alias	EC 2.1.1.319; Histone-arginine N-methyltransferase PRMT1; Interferon receptor 1-bound protein 4
Gene ID	3276
Gene Symbol	PRMT1
Gene Alias	HMT2; HRMT1L2; IR1B4
TTD	T16808: Clinical Trial target
Pfam	PF13649
GO	0042802:identical protein binding 0005634:nucleus 0042054:histone methyltransferase activity 0008170:N-methyltransferase activity 0005829:cytosol 0051260:protein homooligomerization 0006977:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 0008327:methyl-CpG binding 0045652:regulation of megakaryocyte differentiation 0008284:positive regulation of cell population proliferation 0045648:positive regulation of erythrocyte differentiation 0043985:histone H4-R3 methylation 0008276:protein methyltransferase activity 0031175:neuron projection development 0006479:protein methylation 0035241:protein-arginine omega-N monomethyltransferase activity 0019899:enzyme binding 0046985:positive regulation of hemoglobin biosynthetic process 0034709:methylosome 0001701:in utero embryonic development 0048273:mitogen-activated protein kinase p38 binding 0003723:RNA binding 1900745:positive regulation of p38MAPK cascade 0018216:peptidyl-arginine methylation 0005737:cytoplasm 0005654:nucleoplasm 0008168:methyltransferase activity 0016274:protein-arginine N-methyltransferase activity 0007166:cell surface receptor signaling pathway 0016571:histone methylation 0045653:negative regulation of megakaryocyte differentiation 0044020:histone methyltransferase activity (H4-R3 specific) 1904047:S-adenosyl-L-methionine binding 0035242:protein-arginine omega-N asymmetric methyltransferase activity
PDB	6NT2
Drugbank	DB01752
KEGG	hsa:3276

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Name: (2S)-2-Amino-5-[[Amino(Dimethylamino)Methylidene]Amino]Pentanoic Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens