Compound Description
| ID: C1186 | Common name: (2S)-2-Amino-5-[[Amino(Dimethylamino)Methylidene]Amino]Pentanoic Acid |
| IUPAC: (2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid | CAS: CAS:30315-93-6 |
| Chembl ID: CHEMBL457530 | Pubchem ID: CID:123831 |
| Formula: C8H18N4O2 | TCM-ID: TCMC81 |
| Smiles: CN(C)C(=NCCCC(C(=O)O)N)N | |
| Alias:
Ornithine, N5-(N,N-dimethylamidino)-, L-;
N5-[(Dimethylamino)iminomethyl]-L-ornithine; (2S)-2-Amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid; (S)-2-Amino-5-(3,3-dimethylguanidino)pentanoic acid; ADMA; Asymmetric dimethylarginine; Dimethyl-L-arginine; L-NG,NG-Dimethylarginine; NG,NG-Dimethylarginine |
Structure:
|
Related Targets (Total: 15)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
A | 2 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
A | 13 Reference(s) |
| T24U57 | E-selectin | SELE |
P16581 |
A | 1 Reference(s) |
| T99DG6 | Acyl-coenzyme A thioesterase THEM4 | THEM4 |
Q5T1C6 |
A | 1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
A | 1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
A | 1 Reference(s) |
| T68WYW | von Willebrand factor | VWF |
P04275 |
A | 1 Reference(s) |
| T70VMI | Nitric oxide synthase, brain | NOS1 |
P29475 |
A | 1 Reference(s) |
| T09K8S | Protein arginine N-methyltransferase 1 | PRMT1 |
Q99873 |
B | 1 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
B | 1 Reference(s) |
| T89GFN | Macrophage migration inhibitory factor | MIF |
P14174 |
C | 1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
C | 1 Reference(s) |
| T07RPB | NA | NOS2B |
NA |
C | 1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
C | 1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 2)
Ckey description of the interaction between compound and target