HIT-result

Type	Detail
Target ID	T10H9X
Protein Name	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Uniprot ID	O15294
Protein Name Alias	EC 2.4.1.255; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGT
Gene ID	8473
Gene Symbol	OGT
Gene Alias	NA
TTD	NA
Pfam	PF00515 ; PF13844 ; PF13181
GO	0005634:nucleus 0006493:protein O-linked glycosylation 0061087:positive regulation of histone H3-K27 methylation 0005829:cytosol 0043984:histone H4-K16 acetylation 0120162:positive regulation of cold-induced thermogenesis 0048015:phosphatidylinositol-mediated signaling 0016262:protein N-acetylglucosaminyltransferase activity 0097363:protein O-GlcNAc transferase activity 0046626:regulation of insulin receptor signaling pathway 0006915:apoptotic process 0006110:regulation of glycolytic process 0035020:regulation of Rac protein signal transduction 0005547:phosphatidylinositol-3,4,5-trisphosphate binding 0000123:histone acetyltransferase complex 0043981:histone H4-K5 acetylation 0031397:negative regulation of protein ubiquitination 0043982:histone H4-K8 acetylation 0032435:negative regulation of proteasomal ubiquitin-dependent protein catabolic process 0005886:plasma membrane 0032922:circadian regulation of gene expression 0031966:mitochondrial membrane 0006111:regulation of gluconeogenesis 0007584:response to nutrient 0008375:acetylglucosaminyltransferase activity 0032991:protein-containing complex 0080182:histone H3-K4 trimethylation 0045862:positive regulation of proteolysis 0007165:signal transduction 0016485:protein processing 0016032:viral process 0006357:regulation of transcription by RNA polymerase II 0032868:response to insulin 0005654:nucleoplasm 0042995:cell projection 0016579:protein deubiquitination 0045944:positive regulation of transcription by RNA polymerase II 0060544:regulation of necroptotic process 0017122:protein N-acetylglucosaminyltransferase complex
PDB	4AY6 ; 4GZ5 ; 4XIF ; 4AY5 ; 5VIF ; 6IBO ; 4N3A ; 6MA2 ; 4XI9 ; 5HGV ; 5VIE ; 4N3C ; 6EOU ; 3PE3 ; 4GYY ; 3TAX ; 4N39 ; 5LWV ; 5LVV ; 5NPS ; 6MA3 ; 1W3B ; 6E37 ; 4N3B ; 4GZ6 ; 6Q4M ; 4CDR ; 6MA4 ; 6TKA ; 5NPR ; 4GYW ; 6MA1 ; 5BNW ; 6MA5 ; 5C1D ; 3PE4 ; 4GZ3
Drugbank	NA
KEGG	hsa:8473

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Name: Silibinin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0095	Gou Qi Zi	枸杞子	Chinese wolfberry fruit	Lycium chinense
H0094	Gou Qi	枸杞	Chinese wolfberry fruit	Lycium chinense
H0484	Shui Fei Ji	水飞蓟	St marys	Silybum marianum