HIT-result

Type	Detail
Target ID	T10HXK
Protein Name	Cytochrome P450 11B1, mitochondrial
Uniprot ID	P15538
Protein Name Alias	CYPXIB1; Cytochrome P-450c11; Cytochrome P450C11; Steroid 11-beta-hydroxylase, CYP11B1; EC 1.14.15.4
Gene ID	1584
Gene Symbol	CYP11B1
Gene Alias	S11BH
TTD	T84621: Successful target
Pfam	PF00067
GO	0006700:C21-steroid hormone biosynthetic process 0016125:sterol metabolic process 0071375:cellular response to peptide hormone stimulus 0008217:regulation of blood pressure 0034650:cortisol metabolic process 0004507:steroid 11-beta-monooxygenase activity 0008203:cholesterol metabolic process 0042593:glucose homeostasis 0034651:cortisol biosynthetic process 0006704:glucocorticoid biosynthetic process 0005506:iron ion binding 0047783:corticosterone 18-monooxygenase activity 0020037:heme binding 0005739:mitochondrion 0006955:immune response 0032870:cellular response to hormone stimulus 0032342:aldosterone biosynthetic process 0005743:mitochondrial inner membrane 0035865:cellular response to potassium ion
PDB	6M7X
Drugbank	DB01110 ; DB00741 ; DB01026 ; DB01388 ; DB14544 ; DB00648 ; DB14543 ; DB14540 ; DB14545 ; DB01011 ; DB04630 ; DB05667 ; DB11837 ; DB14649 ; DB01234 ; DB00252 ; DB00292 ; DB00501 ; DB14539 ; DB00421
KEGG	hsa:1584

Target Description