Target Description

Type Detail
Target ID T10R1D
Protein Name Copper-transporting ATPase 1
Uniprot ID Q04656
Protein Name Alias EC 7.2.2.8;  Copper pump 1;  Menkes disease-associated protein
Gene ID 538
Gene Symbol ATP7A
Gene Alias MC1;  MNK
TTD NA
Pfam PF00403
GO
0042093:T-helper cell differentiation

1904959:regulation of cytochrome-c oxidase activity

0010468:regulation of gene expression

0032773:positive regulation of monophenol monooxygenase activity

0033162:melanosome membrane

0006878:cellular copper ion homeostasis

0006825:copper ion transport

0005783:endoplasmic reticulum

0019430:removal of superoxide radicals

0051087:chaperone binding

0016021:integral component of membrane

0034760:negative regulation of iron ion transmembrane transport

0030140:trans-Golgi network transport vesicle

0001974:blood vessel remodeling

0051542:elastin biosynthetic process

0071276:cellular response to cadmium ion

0071281:cellular response to iron ion

0043085:positive regulation of catalytic activity

0006584:catecholamine metabolic process

0071230:cellular response to amino acid stimulus

0010592:positive regulation of lamellipodium assembly

0030424:axon

0005802:trans-Golgi network

0007005:mitochondrion organization

0016532:superoxide dismutase copper chaperone activity

0045793:positive regulation of cell size

0005829:cytosol

0071456:cellular response to hypoxia

0005507:copper ion binding

0007626:locomotory behavior

0019730:antimicrobial humoral response

0043005:neuron projection

0005524:ATP binding

0048471:perinuclear region of cytoplasm

0021702:cerebellar Purkinje cell differentiation

0042415:norepinephrine metabolic process

0045121:membrane raft

0007595:lactation

0030199:collagen fibril organization

0021954:central nervous system neuron development

0031901:early endosome membrane

0048286:lung alveolus development

0034220:ion transmembrane transport

0042417:dopamine metabolic process

0010043:response to zinc ion

0071280:cellular response to copper ion

0036120:cellular response to platelet-derived growth factor stimulus

0015677:copper ion import

0007565:female pregnancy

0010041:response to iron(III) ion

0001568:blood vessel development

0005634:nucleus

0005770:late endosome

0048023:positive regulation of melanin biosynthetic process

0016324:apical plasma membrane

0042414:epinephrine metabolic process

0071284:cellular response to lead ion

0001889:liver development

0050679:positive regulation of epithelial cell proliferation

0030198:extracellular matrix organization

0042428:serotonin metabolic process

0001701:in utero embryonic development

0002082:regulation of oxidative phosphorylation

0031252:cell leading edge

0031526:brush border membrane

0043204:perikaryon

0016020:membrane

0043473:pigmentation

0048812:neuron projection morphogenesis

0043588:skin development

0031069:hair follicle morphogenesis

0005902:microvillus

0030425:dendrite

0071236:cellular response to antibiotic

0006568:tryptophan metabolic process

0010042:response to manganese ion

0071279:cellular response to cobalt ion

1904754:positive regulation of vascular associated smooth muscle cell migration

0048251:elastic fiber assembly

0051216:cartilage development

0021860:pyramidal neuron development

0005886:plasma membrane

0030141:secretory granule

0051353:positive regulation of oxidoreductase activity

0018205:peptidyl-lysine modification

0060003:copper ion export

1903136:cuprous ion binding

0010273:detoxification of copper ion

0005794:Golgi apparatus

0030670:phagocytic vesicle membrane

0005375:copper ion transmembrane transporter activity

0043025:neuronal cell body

0016323:basolateral plasma membrane

0043682:P-type divalent copper transporter activity

0032767:copper-dependent protein binding

1903036:positive regulation of response to wounding

0032588:trans-Golgi network membrane

PDB 1S6U ; 1YJR ; 1YJU ; 2KIJ ; 2K1R ; 1YJV ; 1AW0 ; 2G9O ; 1S6O ; 2KMX ; 2GA7 ; 1KVI ; 1Y3K ; 2AW0 ; 1YJT ; 1KVJ ; 2KMV ; 1Y3J ; 3CJK ; 5T7L ; 1Q8L
Drugbank DB00958 ; DB00515 ; DB00526 ; DB09130
KEGG hsa:538

Related Compounds  (Total: 1)

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C0281
Name: Paclitaxel


Related Herbs  (Total: 6)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0515 Suan Shi Liu酸石榴 PomegranatePunica granatum
H0462 Shi Liu石榴 Pomegranate fruitPunica granatum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0463 Shi Liu Pi石榴皮 Pomegranate peelPunica granatum
H0464 Shi Liu Zi石榴子 NAPunica granatum