HIT-result

Type	Detail
Target ID	T10WID
Protein Name	Pro-adrenomedullin [Cleaved into: Adrenomedullin
Uniprot ID	P35318
Protein Name Alias	AM; ProAM N-terminal 20 peptide; PAMP; ProAM-N20
Gene ID	133
Gene Symbol	ADM
Gene Alias	AM
TTD	T20629: Research target
Pfam	PF00214
GO	0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway 0002026:regulation of the force of heart contraction 0045766:positive regulation of angiogenesis 0045906:negative regulation of vasoconstriction 0046879:hormone secretion 0097647:amylin receptor signaling pathway 0005179:hormone activity 0097084:vascular associated smooth muscle cell development 0006954:inflammatory response 0009611:response to wounding 0048589:developmental growth 0032496:response to lipopolysaccharide 0007204:positive regulation of cytosolic calcium ion concentration 0009409:response to cold 0005615:extracellular space 0061844:antimicrobial humoral immune response mediated by antimicrobial peptide 0051384:response to glucocorticoid 0050829:defense response to Gram-negative bacterium 0007507:heart development 0007165:signal transduction 1990410:adrenomedullin receptor signaling pathway 0031102:neuron projection regeneration 0031623:receptor internalization 0001666:response to hypoxia 0008285:negative regulation of cell population proliferation 0031100:animal organ regeneration 0010460:positive regulation of heart rate 0001570:vasculogenesis 0060670:branching involved in labyrinthine layer morphogenesis 0001843:neural tube closure 0042475:odontogenesis of dentin-containing tooth 2001214:positive regulation of vasculogenesis 0002862:negative regulation of inflammatory response to antigenic stimulus 0035809:regulation of urine volume 0043065:positive regulation of apoptotic process 0002031:G protein-coupled receptor internalization 0005576:extracellular region 0005102:signaling receptor binding 0031700:adrenomedullin receptor binding 0008209:androgen metabolic process 0050830:defense response to Gram-positive bacterium 0043116:negative regulation of vascular permeability 0007186:G protein-coupled receptor signaling pathway 0042594:response to starvation 0007565:female pregnancy 0007568:aging 0008284:positive regulation of cell population proliferation 0060712:spongiotrophoblast layer development 2000184:positive regulation of progesterone biosynthetic process 0003073:regulation of systemic arterial blood pressure 0005737:cytoplasm 0032868:response to insulin 0019731:antibacterial humoral response
PDB	6UUN ; 2FLY ; 5V6Y ; 6V2E ; 2L7S ; 4RWF ; 6UUS
Drugbank	NA
KEGG	hsa:133

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Name: Papaverine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H0276	Mu Zhao	木爪	Papayas	Carica papaya
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum