HIT-result

Type	Detail
Target ID	T13JNR
Protein Name	E3 ubiquitin-protein ligase MYLIP
Uniprot ID	Q8WY64
Protein Name Alias	EC 2.3.2.27; Inducible degrader of the LDL-receptor; Idol; Myosin regulatory light chain interacting protein; MIR; RING-type E3 ubiquitin transferase MYLIP
Gene ID	29116
Gene Symbol	MYLIP
Gene Alias	BZF1; IDOL
TTD	NA
Pfam	PF09379 ; PF00373 ; PF09380
GO	0016567:protein ubiquitination 0004842:ubiquitin-protein transferase activity 0008092:cytoskeletal protein binding 0005829:cytosol 0032802:low-density lipoprotein particle receptor catabolic process 0007399:nervous system development 0032803:regulation of low-density lipoprotein particle receptor catabolic process 0006511:ubiquitin-dependent protein catabolic process 0031648:protein destabilization 0005886:plasma membrane 0005856:cytoskeleton 0042632:cholesterol homeostasis 0000209:protein polyubiquitination 0045732:positive regulation of protein catabolic process 0010977:negative regulation of neuron projection development 0046872:metal ion binding 0061630:ubiquitin protein ligase activity 0010989:negative regulation of low-density lipoprotein particle clearance 0030522:intracellular receptor signaling pathway
PDB	6QLZ ; 2YHO ; 2YHN ; 6QLY
Drugbank	NA
KEGG	hsa:29116

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens

Target Description