HIT-result

Type	Detail
Target ID	T14JBS
Protein Name	Glutamate receptor 2
Uniprot ID	P42262
Protein Name Alias	GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2
Gene ID	2891
Gene Symbol	GRIA2
Gene Alias	GLUR2
TTD	T42392: Successful target
Pfam	PF10613 ; PF00060 ; PF01094
GO	0005789:endoplasmic reticulum membrane 0004970:ionotropic glutamate receptor activity 0030425:dendrite 0032281:AMPA glutamate receptor complex 0038023:signaling receptor activity 0007268:chemical synaptic transmission 0043197:dendritic spine 2000310:regulation of NMDA receptor activity 0098843:postsynaptic endocytic zone 0043025:neuronal cell body 0060076:excitatory synapse 0098794:postsynapse 0009897:external side of plasma membrane 0015276:ligand-gated ion channel activity 0005886:plasma membrane 0032279:asymmetric synapse 0005887:integral component of plasma membrane 0035235:ionotropic glutamate receptor signaling pathway 0004971:AMPA glutamate receptor activity 0098839:postsynaptic density membrane 0035249:synaptic transmission, glutamatergic 0014069:postsynaptic density 0007165:signal transduction 0030666:endocytic vesicle membrane 0001540:amyloid-beta binding
PDB	2WJX ; 3R7X ; 5YBG ; 3UA8 ; 5ZG0 ; 2WJW ; 5ZG2 ; 5ZG1 ; 2XHD ; 3RN8 ; 5H8S ; 3RNN ; 5YBF ; 5ZG3
Drugbank	DB01352 ; DB00794 ; DB00237 ; DB03759 ; DB01355 ; DB01174 ; DB02818 ; DB01496 ; DB05047 ; DB01354 ; DB03240 ; DB08305 ; DB01346 ; DB04129 ; DB02347 ; DB00463 ; DB04798 ; DB00898 ; DB04152 ; DB01351 ; DB02999 ; DB08303 ; DB01664 ; DB02966 ; DB04000 ; DB00312 ; DB04982 ; DB00306 ; DB13146 ; DB02057 ; DB00142 ; DB00599 ; DB04599 ; DB07455 ; DB03319 ; DB01483 ; DB08304 ; DB01353 ; DB00241 ; DB00849 ; DB00418 ; DB07598
KEGG	hsa:2891

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 0)