HIT-result

Type	Detail
Target ID	T15M1G
Protein Name	CREB-binding protein
Uniprot ID	Q92793
Protein Name Alias	Histone lysine acetyltransferase CREBBP; EC 2.3.1.48; Protein-lysine acetyltransferase CREBBP; EC 2.3.1.-
Gene ID	1387
Gene Symbol	CREBBP
Gene Alias	CBP
TTD	T03634: Clinical Trial target
Pfam	PF06001 ; PF08214 ; PF02172 ; PF09030 ; PF00439 ; PF00569 ; PF02135
GO	0006367:transcription initiation from RNA polymerase II promoter 0005634:nucleus 0030511:positive regulation of transforming growth factor beta receptor signaling pathway 0045637:regulation of myeloid cell differentiation 0001085:RNA polymerase II transcription factor binding 0007221:positive regulation of transcription of Notch receptor target 0031648:protein destabilization 0016604:nuclear body 0003714:transcription corepressor activity 0061418:regulation of transcription from RNA polymerase II promoter in response to hypoxia 0008270:zinc ion binding 0002039:p53 binding 0016573:histone acetylation 0018076:N-terminal peptidyl-lysine acetylation 0019216:regulation of lipid metabolic process 0065003:protein-containing complex assembly 0042592:homeostatic process 0006473:protein acetylation 0005654:nucleoplasm 0045893:positive regulation of transcription, DNA-templated 0002223:stimulatory C-type lectin receptor signaling pathway 0045944:positive regulation of transcription by RNA polymerase II 0003682:chromatin binding 0007165:signal transduction 0000123:histone acetyltransferase complex 0061733:peptide-lysine-N-acetyltransferase activity 0042733:embryonic digit morphogenesis 0001666:response to hypoxia 0034644:cellular response to UV 0000122:negative regulation of transcription by RNA polymerase II 0016407:acetyltransferase activity 0001102:RNA polymerase II activating transcription factor binding 0008134:transcription factor binding 0003713:transcription coactivator activity 0003684:damaged DNA binding 0032481:positive regulation of type I interferon production 1904837:beta-catenin-TCF complex assembly 0007219:Notch signaling pathway 0042981:regulation of apoptotic process 0045747:positive regulation of Notch signaling pathway 0048511:rhythmic process 0008589:regulation of smoothened signaling pathway 0016032:viral process 1900034:regulation of cellular response to heat 0005737:cytoplasm 0006355:regulation of transcription, DNA-templated 0031490:chromatin DNA binding 0043426:MRF binding 0000785:chromatin 1990258:histone glutamine methylation 0005667:transcription regulator complex 0004402:histone acetyltransferase activity
PDB	4N3W ; 5SVH ; 4A9K ; 5W0L ; 5I8G ; 6SXX ; 2RNY ; 1RDT ; 4NR5 ; 5MME ; 6FQU ; 1WO5 ; 5KTW ; 5KTX ; 6FR0 ; 1ZOQ ; 6YIJ ; 4NYV ; 4NR4 ; 5DBM ; 5I83 ; 1WO6 ; 5MMG ; 6AY5 ; 5JEM ; 5ENG ; 5MPN ; 4N4F ; 3DWY ; 1WO7 ; 5W0E ; 3P1E ; 6ES6 ; 5OWK ; 2LXS ; 6FQT ; 2D82 ; 4WHU ; 3P1D ; 1WO3 ; 6FQO ; 7CO1 ; 5GH9 ; 6YIM ; 6SQM ; 4YK0 ; 5I89 ; 5MQG ; 6YIL ; 2KWF ; 6AXQ ; 3P1C ; 5MQK ; 6DMK ; 1WO4 ; 6SQF ; 6ALB ; 5W0Q ; 3SVH ; 5LPJ ; 6SQE ; 4OUF ; 2KJE ; 7JFM ; 6ALC ; 5NLK ; 2L84 ; 3P1F ; 6QST ; 6FRF ; 6YIK ; 5J0D ; 5MPZ ; 5H85 ; 6ES7 ; 1JSP ; 5XXH ; 2LXT ; 5CGP ; 5I8B ; 6ES5 ; 5MPK ; 5LPL ; 4NR6 ; 4NYX ; 1LIQ ; 5MQE ; 7JFL ; 5I86 ; 5NRW ; 5KTU ; 2L85 ; 4NYW ; 4TS8 ; 5TB6 ; 6AY3 ; 2N1A ; 4TQN ; 5W0F ; 4NR7 ; 5EP7 ; 5EIC ; 5NU3
Drugbank	DB08655
KEGG	hsa:1387

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Name: Anacardic Acid

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Name: Anacardic Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1055	Bai Guo Ren	白果仁	ginkgo	Ginkgo biloba
H0750	Yin Xing Ye	银杏叶	Folium ginkgo	Ginkgo biloba
H1169	He Ye	荷叶	Hindu lotus leaf	Nelumbo nucifera
H0140	Lian Zi	莲子	Hindu lotus seed	Nelumbo nucifera
H1164	He Geng	荷梗	Hindu lotus petiole	Nelumbo nucifera
H0304	Ou Pian	藕片	Hindu lotus large rhizome	Nelumbo nucifera
H0302	Ou Fen	藕粉	Hindu lotus large rhizome	Nelumbo nucifera
H0141	Lian Zi Xin	莲子心	Hindu lotus plumule	Nelumbo nucifera
H1051	Bai Guo	白果	Ginkgo nut	Ginkgo biloba
H0301	Ou	藕	Hindu lotus large rhizome	Nelumbo nucifera