HIT-result

Type	Detail
Target ID	T16SLA
Protein Name	Mothers against decapentaplegic homolog 6
Uniprot ID	O43541
Protein Name Alias	MAD homolog 6; Mothers against DPP homolog 6; SMAD family member 6; SMAD 6; Smad6; hSMAD6
Gene ID	4091
Gene Symbol	SMAD6
Gene Alias	MADH6
TTD	T92714: Research target
Pfam	PF03165 ; PF03166
GO	1902895:positive regulation of pri-miRNA transcription by RNA polymerase II 0042802:identical protein binding 0005634:nucleus 0030509:BMP signaling pathway 0071144:heteromeric SMAD protein complex 0007179:transforming growth factor beta receptor signaling pathway 0035904:aorta development 0003184:pulmonary valve morphogenesis 0043627:response to estrogen 0034616:response to laminar fluid shear stress 0005829:cytosol 0070698:type I activin receptor binding 0034713:type I transforming growth factor beta receptor binding 0003183:mitral valve morphogenesis 0010991:negative regulation of SMAD protein complex assembly 0003682:chromatin binding 0031625:ubiquitin protein ligase binding 0070410:co-SMAD binding 0001657:ureteric bud development 0003148:outflow tract septum morphogenesis 0006955:immune response 0009653:anatomical structure morphogenesis 0008285:negative regulation of cell population proliferation 0030279:negative regulation of ossification 0045444:fat cell differentiation 0140416:transcription regulator inhibitor activity 0005737:cytoplasm 0030154:cell differentiation 0070411:I-SMAD binding 0000785:chromatin 0003281:ventricular septum development 0000976:transcription regulatory region sequence-specific DNA binding 0003180:aortic valve morphogenesis 0030514:negative regulation of BMP signaling pathway 0060395:SMAD protein signal transduction 0030512:negative regulation of transforming growth factor beta receptor signaling pathway 0032991:protein-containing complex 0016604:nuclear body 0045668:negative regulation of osteoblast differentiation 0070412:R-SMAD binding 0005794:Golgi apparatus 0060976:coronary vasculature development 0060394:negative regulation of pathway-restricted SMAD protein phosphorylation 0031589:cell-substrate adhesion 0032496:response to lipopolysaccharide 0005654:nucleoplasm 0046872:metal ion binding 0007352:zygotic specification of dorsal/ventral axis 0043066:negative regulation of apoptotic process
PDB	NA
Drugbank	NA
KEGG	hsa:4091

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Name: Melatonin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens