HIT-result

Type	Detail
Target ID	T16UPB
Protein Name	STE20/SPS1-related proline-alanine-rich protein kinase
Uniprot ID	Q9UEW8
Protein Name Alias	Ste-20-related kinase; EC 2.7.11.1; DCHT; Serine/threonine-protein kinase 39
Gene ID	27347
Gene Symbol	STK39
Gene Alias	SPAK
TTD	T67837: Research target
Pfam	PF00069 ; PF12202
GO	0004674:protein serine/threonine kinase activity 0035556:intracellular signal transduction 1901017:negative regulation of potassium ion transmembrane transporter activity 0005524:ATP binding 1905408:negative regulation of creatine transmembrane transporter activity 0018107:peptidyl-threonine phosphorylation 0005856:cytoskeleton 0006468:protein phosphorylation 2000650:negative regulation of sodium ion transmembrane transporter activity 0043268:positive regulation of potassium ion transport 0106311:protein threonine kinase activity 0050801:ion homeostasis 0018105:peptidyl-serine phosphorylation 0008217:regulation of blood pressure 0071476:cellular hypotonic response 0005829:cytosol 0046777:protein autophosphorylation 0005654:nucleoplasm 0038146:chemokine (C-X-C motif) ligand 12 signaling pathway 0036438:maintenance of lens transparency 1901380:negative regulation of potassium ion transmembrane transport 1990869:cellular response to chemokine 0019898:extrinsic component of membrane 0016323:basolateral plasma membrane 0019901:protein kinase binding 0032414:positive regulation of ion transmembrane transporter activity 0106310:protein serine kinase activity 0043231:intracellular membrane-bounded organelle 0000187:activation of MAPK activity 0007165:signal transduction 0090188:negative regulation of pancreatic juice secretion 0016301:kinase activity 0016324:apical plasma membrane 0010820:positive regulation of T cell chemotaxis 0050727:regulation of inflammatory response
PDB	NA
Drugbank	DB12010
KEGG	hsa:27347

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 0)