HIT-result

Type	Detail
Target ID	T18T1M
Protein Name	Tyrosine-protein kinase Mer
Uniprot ID	Q12866
Protein Name Alias	EC 2.7.10.1; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK
Gene ID	10461
Gene Symbol	MERTK
Gene Alias	MER
TTD	T55781: Clinical Trial target
Pfam	PF00041 ; PF00047 ; PF07714
GO	0005524:ATP binding 0043491:protein kinase B signaling 0051250:negative regulation of lymphocyte activation 0006909:phagocytosis 0033674:positive regulation of kinase activity 0034446:substrate adhesion-dependent cell spreading 0060041:retina development in camera-type eye 0001818:negative regulation of cytokine production 0007283:spermatogenesis 0007169:transmembrane receptor protein tyrosine kinase signaling pathway 0097350:neutrophil clearance 0004714:transmembrane receptor protein tyrosine kinase activity 0005887:integral component of plasma membrane 0007166:cell surface receptor signaling pathway 0001750:photoreceptor outer segment 0005737:cytoplasm 0016477:cell migration 0050900:leukocyte migration 0005615:extracellular space 0006468:protein phosphorylation 0032940:secretion by cell 0060068:vagina development 0007275:multicellular organism development 0030168:platelet activation 0001779:natural killer cell differentiation 0016028:rhabdomere 0005886:plasma membrane 0050766:positive regulation of phagocytosis 0043235:receptor complex 0007267:cell-cell signaling 2000107:negative regulation of leukocyte apoptotic process 0007399:nervous system development
PDB	2DBJ ; 5K0X ; 2P0C ; 3BPR ; 3BRB ; 5TD2 ; 7AB2 ; 5K0K ; 7AAY ; 4MH7 ; 7AB1 ; 7AB0 ; 4M3Q ; 7AAX ; 3TCP ; 4MHA ; 7CQE ; 5U6C ; 5TC0 ; 6MEP ; 7AAZ
Drugbank	DB08325 ; DB12010
KEGG	hsa:10461

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Name: Sulforaphane

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0125	Lai Fu	莱菔	Garden radish	Raphanus sativus
H0466	Cai Fu Zi	菜菔子	Semen raphani	Raphanus sativus
H0960	Dang Shen Qing Gao	党参清膏	Root of hairy asiabell	Codonopsis pilosula
H0958	Dang Shen	党参	Pilose asiabell	Codonopsis pilosula
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0126	Lai Fu Zi	莱菔子	Garden radish seed	Raphanus sativus