HIT-result

Type	Detail
Target ID	T18YTV
Protein Name	Natural resistance-associated macrophage protein 2
Uniprot ID	P49281
Protein Name Alias	NRAMP 2; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; Solute carrier family 11 member 2
Gene ID	4891
Gene Symbol	SLC11A2
Gene Alias	DCT1; DMT1; NRAMP2
TTD	T22717: Research target
Pfam	PF01566
GO	0015675:nickel cation transport 0006825:copper ion transport 0015100:vanadium ion transmembrane transporter activity 0009986:cell surface 0045178:basal part of cell 0006783:heme biosynthetic process 0034755:iron ion transmembrane transport 0001666:response to hypoxia 0016020:membrane 0055037:recycling endosome 0003032:detection of oxygen 0006824:cobalt ion transport 0071577:zinc ion transmembrane transport 0031902:late endosome membrane 0015295:solute:proton symporter activity 0015087:cobalt ion transmembrane transporter activity 0070826:paraferritin complex 0048813:dendrite morphogenesis 0060586:multicellular organismal iron ion homeostasis 0046915:transition metal ion transmembrane transporter activity 0005764:lysosome 0015099:nickel cation transmembrane transporter activity 0006828:manganese ion transport 0005773:vacuole 0045177:apical part of cell 0022890:inorganic cation transmembrane transporter activity 0005886:plasma membrane 0005765:lysosomal membrane 0005375:copper ion transmembrane transporter activity 0070574:cadmium ion transmembrane transport 0005384:manganese ion transmembrane transporter activity 0005887:integral component of plasma membrane 0005802:trans-Golgi network 0005737:cytoplasm 0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process 0015094:lead ion transmembrane transporter activity 0048471:perinuclear region of cytoplasm 0015086:cadmium ion transmembrane transporter activity 0098656:anion transmembrane transport 0015093:ferrous iron transmembrane transporter activity 0005385:zinc ion transmembrane transporter activity 1905394:retromer complex binding 0005739:mitochondrion 0005741:mitochondrial outer membrane 0015676:vanadium ion transport 0046870:cadmium ion binding 0034599:cellular response to oxidative stress 0005634:nucleus 0031526:brush border membrane 0070588:calcium ion transmembrane transport 0048821:erythrocyte development 0006826:iron ion transport 0007611:learning or memory 0006879:cellular iron ion homeostasis 0005769:early endosome 0033212:iron import into cell 0005381:iron ion transmembrane transporter activity 0015692:lead ion transport 0010039:response to iron ion 0005770:late endosome 0031410:cytoplasmic vesicle 0016324:apical plasma membrane 1903561:extracellular vesicle
PDB	5F0P ; 5F0L ; 5F0M
Drugbank	DB09130 ; DB13257 ; DB06796 ; DB15598 ; DB14520
KEGG	hsa:4891

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Name: inulin

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