Target Description

Type Detail
Target ID T19BRL
Protein Name Interferon-induced helicase C domain-containing protein 1
Uniprot ID Q9BYX4
Protein Name Alias EC 3.6.4.13;  Clinically amyopathic dermatomyositis autoantigen 140 kDa;  CADM-140 autoantigen;  Helicase with 2 CARD domains;  Helicard;  Interferon-induced with helicase C domain protein 1;  Melanoma differentiation-associated protein 5;  MDA-5;  Murabutide down-regulated protein;  RIG-I-like receptor 2;  RLR-2;  RNA helicase-DEAD box protein 116
Gene ID 64135
Gene Symbol IFIH1
Gene Alias MDA5;  RH116
TTD NA
Pfam PF16739 ; PF18119 ; PF04851 ; PF00271 ; PF11648
GO
0003677:DNA binding

0042802:identical protein binding

0005634:nucleus

0071360:cellular response to exogenous dsRNA

0003724:RNA helicase activity

0051607:defense response to virus

0039530:MDA-5 signaling pathway

0005829:cytosol

0032755:positive regulation of interleukin-6 production

0009597:detection of virus

0032727:positive regulation of interferon-alpha production

0003725:double-stranded RNA binding

0005524:ATP binding

0032480:negative regulation of type I interferon production

0034344:regulation of type III interferon production

0016925:protein sumoylation

0032728:positive regulation of interferon-beta production

0009615:response to virus

0032760:positive regulation of tumor necrosis factor production

0008270:zinc ion binding

0039528:cytoplasmic pattern recognition receptor signaling pathway in response to virus

0005737:cytoplasm

0043021:ribonucleoprotein complex binding

0016032:viral process

0016579:protein deubiquitination

0060760:positive regulation of response to cytokine stimulus

0003727:single-stranded RNA binding

0045087:innate immune response

PDB 3B6E ; 3GA3 ; 7JL0 ; 2RQB ; 4GL2 ; 7JL2
Drugbank NA
KEGG hsa:64135

Related Compounds  (Total: 1)

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C0210
Name: Melatonin


Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens